S1 螺旋线是 VSP 的 VIP。

IF 3.3 2区医学 Q1 PHYSIOLOGY

Journal of General Physiology Pub Date : 2024-07-01 Epub Date: 2024-06-11 DOI:10.1085/jgp.202413612

Ben Short

引用次数: 0

摘要

JGP 研究（Rayaprolu 等人，https://doi.org/10.1085/jgp.202313467）表明，S1 跨膜结构域中的疏水残基可调节电压传感器的运动和电压传感磷酸酶的酶活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The S1 helix is a VIP in VSP.

JGP study (Rayaprolu et al. https://doi.org/10.1085/jgp.202313467) shows that hydrophobic residues in the S1 transmembrane domain modulate the voltage sensor movements and enzymatic activity of voltage-sensing phosphatase.

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来源期刊

Journal of General Physiology 医学-生理学

CiteScore

6.00

自引率

10.50%

发文量

审稿时长

6-12 weeks

期刊介绍： General physiology is the study of biological mechanisms through analytical investigations, which decipher the molecular and cellular mechanisms underlying biological function at all levels of organization. The mission of Journal of General Physiology (JGP) is to publish mechanistic and quantitative molecular and cellular physiology of the highest quality, to provide a best-in-class author experience, and to nurture future generations of independent researchers. The major emphasis is on physiological problems at the cellular and molecular level.