David Aguirre-Villarreal, Mario Andrés de Jesús Leal-Villarreal, Ignacio García-Juárez, Eduardo R Argaiz, Abhilash Koratala
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引用次数: 0
摘要
肝硬化是一种发病率和死亡率都很高的疾病,本文深入探讨了肝硬化急性肾损伤(AKI)所面临的复杂挑战。肝硬化患者由于门静脉高压导致血液动力学改变,因此需要区分导致急性肾损伤(AKI)的各种原因,尤其是血液动力学性急性肾损伤。本书引入了 "肝心肾综合征 "这一术语,以概括肝脏、心脏和肾脏之间错综复杂的相互作用。文章强调了在肝硬化 AKI 评估中经常被忽视的心脏功能,揭示了以舒张功能受损为特征的肝硬化心肌病的普遍性。文中对肝肾综合征采用扩容和血管加压的传统经验疗法进行了批判性分析,强调了潜在的风险和患者的不同反应。我们主张对肝硬化患者的 AKI 进行细致入微的评估,其中以护理点超声波检查 (POCUS) 为突出特点。POCUS 的应用包括评估液体耐受性、检测静脉充血和评估心脏功能。
Sound waves and solutions: Point-of-care ultrasonography for acute kidney injury in cirrhosis.
This article delves into the intricate challenges of acute kidney injury (AKI) in cirrhosis, a condition fraught with high morbidity and mortality. The complexities arise from distinguishing between various causes of AKI, particularly hemodynamic AKI, in cirrhotic patients, who experience hemodynamic changes due to portal hypertension. The term "hepatocardiorenal syndrome" is introduced to encapsulate the intricate interplay among the liver, heart, and kidneys. The narrative emphasizes the often-overlooked aspect of cardiac function in AKI assessments in cirrhosis, unveiling the prevalence of cirrhotic cardiomyopathy marked by impaired diastolic function. The conventional empiric approach involving volume expansion and vasopressors for hepatorenal syndrome is critically analyzed, highlighting potential risks and variable patient responses. We advocate for a nuanced algorithm for AKI evaluation in cirrhosis, prominently featuring point-of-care ultrasonography (POCUS). POCUS applications encompass assessing fluid tolerance, detecting venous congestion, and evaluating cardiac function.