框架线圈方向及其形状对基底动脉瘤模型血液动力学的影响。

IF 2.6 4区 医学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
Nisanth Kumar Panneerselvam, B J Sudhir, Santhosh K Kannath, B S V Patnaik
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引用次数: 0

摘要

动脉瘤是动脉的隆起,需要临床治疗方案。由于其固有的优势,血管内线圈填充正成为治疗颅内动脉瘤(IAs)的首选方法。然而,线圈栓塞治疗成功后,存在严重的复发风险。众所周知,最佳的填塞密度会提高治疗效果。血管内线圈栓塞术的主要目的是通过显著减少动脉瘤内血流来实现血流瘀滞,并促进血栓形成。本研究通过数值方法研究了框架线圈方向对动脉瘤内血流动力学的影响。为了分析的目的,使用了栓塞线圈的实际形状,而不是简化的理想线圈形状。通常情况下,框架线圈的细节会在分析中得到解决。然而,框架线圈上方的区域假定充满了多孔介质。目前的模拟结果表明,框架线圈环(FCL)的方向对动脉瘤内的血流动力学有很大影响。与基底动脉瘤出口平行放置的 FCL(线圈 A)可降低动脉瘤内的流速,从而促进血栓形成。涉及该区域的线圈使用堆积密度为 20% 的多孔介质模型建模。模拟结果表明,框架线圈环(FCL)对总体结果有显著影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Influence of framing coil orientation and its shape on the hemodynamics of a basilar aneurysm model.

Influence of framing coil orientation and its shape on the hemodynamics of a basilar aneurysm model.

Aneurysms are bulges of an artery, which require clinical management solutions. Due to the inherent advantages, endovascular coil filling is emerging as the treatment of choice for intracranial aneurysms (IAs). However, after successful treatment of coil embolization, there is a serious risk of recurrence. It is well known that optimal packing density will enhance treatment outcomes. The main objective of endovascular coil embolization is to achieve flow stasis by enabling significant reduction in intra-aneurysmal flow and facilitate thrombus formation. The present study numerically investigates the effect of framing coil orientation on intra-aneurysmal hemodynamics. For the purpose of analysis, actual shape of the embolic coil is used, instead of simplified ideal coil shape. Typically used details of the framing coil are resolved for the analysis. However, region above the framing coil is assumed to be filled with a porous medium. Present simulations have shown that orientation of the framing coil loop (FCL) greatly influences the intra-aneurysmal hemodynamics. The FCLs which were placed parallel to the outlets of basilar tip aneurysm (Coil A) were found to reduce intra-aneurysmal flow velocity that facilitates thrombus formation. Involving the coil for the region is modeled using a porous medium model with a packing density of 20 % . The simulations indicate that the framing coil loop (FCL) has a significant influence on the overall outcome.

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来源期刊
Medical & Biological Engineering & Computing
Medical & Biological Engineering & Computing 医学-工程:生物医学
CiteScore
6.00
自引率
3.10%
发文量
249
审稿时长
3.5 months
期刊介绍: Founded in 1963, Medical & Biological Engineering & Computing (MBEC) continues to serve the biomedical engineering community, covering the entire spectrum of biomedical and clinical engineering. The journal presents exciting and vital experimental and theoretical developments in biomedical science and technology, and reports on advances in computer-based methodologies in these multidisciplinary subjects. The journal also incorporates new and evolving technologies including cellular engineering and molecular imaging. MBEC publishes original research articles as well as reviews and technical notes. Its Rapid Communications category focuses on material of immediate value to the readership, while the Controversies section provides a forum to exchange views on selected issues, stimulating a vigorous and informed debate in this exciting and high profile field. MBEC is an official journal of the International Federation of Medical and Biological Engineering (IFMBE).
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