[中暑的发病机制和治疗策略研究进展]。

Q3 Medicine
Haixin Ma, Yanli Zhu, Jiayan Li, Qiong Liu, Yang Yang
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引用次数: 0

摘要

中暑(HS)又称重度日光性中暑,是最严重的热相关疾病之一,具有起病急、进展快、病情凶险、发病率和死亡率高的特点。中暑的发生和发展与炎症、氧化应激、细胞死亡和凝血功能衰竭等病理生理过程密切相关。随着 HS 致病机制的逐步发现,一些针对其分子调控途径的药物或治疗方法已显示出临床前景。本综述旨在概述有关 HS 类型、致病机制、临床前和临床相关治疗策略的研究进展,并重点介绍 HS 相关生物标记物和治疗靶点的潜在临床应用,以期为 HS 的临床治疗提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Research progress on the pathogenic mechanisms and treatment strategies of heat stroke].

Heat stroke (HS), also known as severe sunstroke, is one of the most serious heat-related disorders, characterized by rapid onset, rapid progression, aggressive condition, and high morbidity and mortality. The occurrence and development of HS are closely related to pathophysiological processes such as inflammation, oxidative stress, cell death, and coagulation failure. With the gradual discovery of the pathogenic mechanisms of HS, some drugs or therapeutic approaches targeting its molecular regulatory pathways have shown clinical promise. This review intends to provide an overview of research advances in HS types, pathogenic mechanisms, preclinical and clinically relevant therapeutic strategies, as well as to highlight the potential clinical applications of HS-related biomarkers and therapeutic targets with a view to informing the clinical management of HS.

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来源期刊
Zhonghua wei zhong bing ji jiu yi xue
Zhonghua wei zhong bing ji jiu yi xue Medicine-Critical Care and Intensive Care Medicine
CiteScore
1.00
自引率
0.00%
发文量
42
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