Mark A Colantonio, Michelle Hartzell, Brooke Shannon, Apoorva Iyer
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引用次数: 0
摘要
阿狄森氏病是一种罕见的自身免疫性疾病，会导致肾上腺受损。众所周知，自身免疫性疾病通常会同时出现。当阿狄森氏病合并自身免疫性甲状腺疾病和/或 1 型糖尿病时，这种疾病被称为自身免疫性多内分泌综合征 II 型，这是一种罕见的内分泌疾病，每 10 万人中大约有 1.4-4.5 人患此病。在此，我们描述了一个临床病例，该病例表现为液体复苏难治性低血压和电解质紊乱，后被诊断为自身免疫性多内分泌综合征 II 型：原发性肾上腺功能不全在临床上可能表现为液体复苏难治性休克。自身免疫性多内分泌综合征 2 型是一种罕见的自身免疫性疾病，每 10 万人中有 1.5-4.5 人发病。
A Silent Cause of Shock: Autoimmune Polyglandular Syndromes.
Addison's disease is a rare, autoimmune condition leading to destruction of the adrenal gland. Autoimmune conditions are known to commonly co-occur. When Addison's disease presents in the setting of autoimmune thyroid disease and/or type 1 diabetes, this condition is termed autoimmune polyendocrine syndrome type II, a rare endocrinopathy found in roughly 1.4-4.5 per 100,000 individuals. Here, we describe a clinical case presenting with hypotension refractory to fluid resuscitation and electrolyte derangements later diagnosed as autoimmune polyendocrine syndrome type II.
Learning points: Primary adrenal insufficiency may present clinically as shock refractory to fluid resuscitation.Autoimmune polyglandular syndrome type 2 is a rare autoimmune condition occurring in 1.5-4.5 per 100,000 individuals.The presence of an underlying autoimmune condition should raise suspicion for multiple concurrent autoimmune conditions.
期刊介绍：
The European Journal of Case Reports in Internal Medicine is an official journal of the European Federation of Internal Medicine (EFIM), representing 35 national societies from 33 European countries. The Journal''s mission is to promote the best medical practice and innovation in the field of acute and general medicine. It also provides a forum for internal medicine doctors where they can share new approaches with the aim of improving diagnostic and clinical skills in this field. EJCRIM welcomes high-quality case reports describing unusual or complex cases that an internist may encounter in everyday practice. The cases should either demonstrate the appropriateness of a diagnostic/therapeutic approach, describe a new procedure or maneuver, or show unusual manifestations of a disease or unexpected reactions. The Journal only accepts and publishes those case reports whose learning points provide new insight and/or contribute to advancing medical knowledge both in terms of diagnostics and therapeutic approaches. Case reports of medical errors, therefore, are also welcome as long as they provide innovative measures on how to prevent them in the current practice (Instructive Errors). The Journal may also consider brief and reasoned reports on issues relevant to the practice of Internal Medicine, as well as Abstracts submitted to the scientific meetings of acknowledged medical societies.
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