病例报告:睾丸旁纺锤形细胞脂肪瘤疑似分化良好的脂肪肉瘤

Kengo Fujiwara, Kengo Fujimoto, Emi Ibuki, Ryo Ishikawa, Yushi Hayashida
{"title":"病例报告:睾丸旁纺锤形细胞脂肪瘤疑似分化良好的脂肪肉瘤","authors":"Kengo Fujiwara, Kengo Fujimoto, Emi Ibuki, Ryo Ishikawa, Yushi Hayashida","doi":"10.3389/fruro.2024.1400674","DOIUrl":null,"url":null,"abstract":"Spindle cell lipoma is a relatively rare benign tumor that can occur in the posterior neck, shoulder, and upper back. Herein, we present a case of intrascrotal spindle cell lipoma in a 71-year-old male who presented with a mass in the left scrotum that had developed over 2 years. Contrast-enhanced computed tomography (CT) revealed a 5.7cm mass accompanying enhanced solid components. Magnetic resonance imaging (MRI) showed a heterogeneous signal intensity. Therefore, a well-differentiated liposarcoma derived from the spermatic cord was suspected; therefore, the patient underwent radical inguinal orchidectomy with high ligation of the spermatic cord. Histopathological examination revealed mature adipocytes and bland-spindle cells. Immunohistochemically, the tumor cells were positive for CD-34 and negative for CDK4, MDM2, and p16. These findings indicated a spindle cell lipoma. Surgical margins were negative. Three months after surgery, no relapse was observed. This case underscores the rarity of para-testicular spindle cell lipoma. While CT and MRI play crucial roles in disease diagnosis, they may not detect all lesions. To prevent overtreatment, it’s essential to also consider pre-surgical examinations and intraoperative findings.","PeriodicalId":73113,"journal":{"name":"Frontiers in urology","volume":"9 20","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Case report: Para-testicular spindle cell lipoma suspected of well-differentiated liposarcoma\",\"authors\":\"Kengo Fujiwara, Kengo Fujimoto, Emi Ibuki, Ryo Ishikawa, Yushi Hayashida\",\"doi\":\"10.3389/fruro.2024.1400674\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Spindle cell lipoma is a relatively rare benign tumor that can occur in the posterior neck, shoulder, and upper back. Herein, we present a case of intrascrotal spindle cell lipoma in a 71-year-old male who presented with a mass in the left scrotum that had developed over 2 years. Contrast-enhanced computed tomography (CT) revealed a 5.7cm mass accompanying enhanced solid components. Magnetic resonance imaging (MRI) showed a heterogeneous signal intensity. Therefore, a well-differentiated liposarcoma derived from the spermatic cord was suspected; therefore, the patient underwent radical inguinal orchidectomy with high ligation of the spermatic cord. Histopathological examination revealed mature adipocytes and bland-spindle cells. Immunohistochemically, the tumor cells were positive for CD-34 and negative for CDK4, MDM2, and p16. These findings indicated a spindle cell lipoma. Surgical margins were negative. Three months after surgery, no relapse was observed. This case underscores the rarity of para-testicular spindle cell lipoma. While CT and MRI play crucial roles in disease diagnosis, they may not detect all lesions. To prevent overtreatment, it’s essential to also consider pre-surgical examinations and intraoperative findings.\",\"PeriodicalId\":73113,\"journal\":{\"name\":\"Frontiers in urology\",\"volume\":\"9 20\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontiers in urology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3389/fruro.2024.1400674\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in urology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3389/fruro.2024.1400674","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

纺锤形细胞脂肪瘤是一种比较罕见的良性肿瘤,可发生在颈后、肩部和上背部。在此,我们介绍了一例阴囊内纺锤形细胞脂肪瘤病例,患者是一名 71 岁男性,因左侧阴囊肿块发展了 2 年而就诊。对比增强计算机断层扫描(CT)显示,肿块 5.7 厘米,伴有增强的实性成分。磁共振成像(MRI)显示信号强度不均匀。因此,患者接受了腹股沟睾丸根治性切除术和精索高位结扎术。组织病理学检查发现了成熟的脂肪细胞和扁平纺锤形细胞。免疫组化结果显示,肿瘤细胞 CD-34 阳性,CDK4、MDM2 和 p16 阴性。这些结果表明这是一个纺锤形细胞脂肪瘤。手术切缘呈阴性。术后三个月未见复发。该病例强调了睾丸旁纺锤形细胞脂肪瘤的罕见性。虽然 CT 和 MRI 在疾病诊断中起着至关重要的作用,但它们可能无法发现所有病变。为防止过度治疗,还必须考虑术前检查和术中发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Case report: Para-testicular spindle cell lipoma suspected of well-differentiated liposarcoma
Spindle cell lipoma is a relatively rare benign tumor that can occur in the posterior neck, shoulder, and upper back. Herein, we present a case of intrascrotal spindle cell lipoma in a 71-year-old male who presented with a mass in the left scrotum that had developed over 2 years. Contrast-enhanced computed tomography (CT) revealed a 5.7cm mass accompanying enhanced solid components. Magnetic resonance imaging (MRI) showed a heterogeneous signal intensity. Therefore, a well-differentiated liposarcoma derived from the spermatic cord was suspected; therefore, the patient underwent radical inguinal orchidectomy with high ligation of the spermatic cord. Histopathological examination revealed mature adipocytes and bland-spindle cells. Immunohistochemically, the tumor cells were positive for CD-34 and negative for CDK4, MDM2, and p16. These findings indicated a spindle cell lipoma. Surgical margins were negative. Three months after surgery, no relapse was observed. This case underscores the rarity of para-testicular spindle cell lipoma. While CT and MRI play crucial roles in disease diagnosis, they may not detect all lesions. To prevent overtreatment, it’s essential to also consider pre-surgical examinations and intraoperative findings.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
0.40
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信