在 A 型解剖中使用冷冻大象:基本原理、创新和陷阱。

Expert review of medical devices Pub Date : 2024-07-01 Epub Date: 2024-06-11 DOI:10.1080/17434440.2024.2365416
Paolo Berretta, Michele Galeazzi, Pietro G Malvindi, Mariano Cefarelli, Jacopo Alfonsi, Olimpia Bifulco, Emanuele Gatta, Marco Di Eusanio
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引用次数: 0

摘要

导言:A型急性主动脉夹层(TA-AAD)是主动脉外科医生面临的巨大挑战。如何建立标准化的手术方法,尤其是确定是否以及何时在同一手术中处理主动脉弓和远端主动脉以及近端主动脉,目前仍不明确:过去十年中,冷冻象鼻躯干(FET)已成为治疗 TA-AAD 的重要方法。在此,我们讨论了冷冻象鼻干手术的基本原理和陷阱,并介绍了最新的创新技术:专家观点:冷冻象鼻躯干术有可能简化复杂的拱形撕裂和破裂患者的拱形重建,优化真腔受压和灌注不良患者的远端真腔灌注,解决远端再入路撕裂,促进假腔血栓形成和晚期主动脉重塑。尽管如此,FET 仍有不可忽视的死亡率和发病率。患者选择、手术专业知识和术后护理仍是确保成功的关键因素。FET 手术的最新创新包括开发可最大限度减少或避免低体温循环骤停的技术,以及采用不同拱形分支配置的新型 FET 装置,以方便后续的主动脉再介入手术。我们相信,这两项进步都有可能改善患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Frozen elephant use in type a dissection: fundamentals, innovations, and pitfalls.

Introduction: Type A acute aortic dissection (TA-AAD) is a great challenge for aortic surgeons. The establishment of a standardized surgical approach, particularly the determination of whether and when to address the aortic arch and the distal aorta in the same operation as the proximal aorta, is still unclear.

Areas covered: Frozen elephant trunk (FET) has emerged as a valuable treatment for TA-AAD over the last decade. Here, we discuss the fundamentals and pitfalls of frozen elephant trunk procedures and present the latest innovations.

Expert opinion: FET has the potential to simplify arch reconstruction in patients with complex arch tears and rupture, optimize perfusion in the distal true lumen for those with a compressed true lumen and malperfusion, address distal reentry tears, and promote false lumen thrombosis and late aortic remodeling. Nevertheless, FET is still associated with non-negligible mortality and morbidity rates. Patient selection, surgical expertise, and postoperative care remain crucial determinants in ensuring successful outcomes. Recent innovations in FET surgery involve the development of techniques to minimize or avoid hypothermic circulatory arrest and new FET devices with different arch branch configurations aiming to facilitate subsequent aortic reinterventions. We believe that both these advancements have the potential to improve patient outcomes.

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