2-氨基-1-(芳基)-5-(芳基氨基甲酰基)-6-氧代-1,6-二氢吡啶-3-羧酸乙酯的合成

IF 1.4 4区化学 Q3 CHEMISTRY, ORGANIC

Chemistry of Heterocyclic Compounds Pub Date : 2024-06-04 DOI:10.1007/s10593-024-03311-5

Anush Kh. Khachatryan, Katya A. Avagyan, Anush A. Sargsyan, Anait G. Simonyan, Henrik A. Panosyan, Armen G. Ayvazyan, Alik E. Badasyan

引用次数: 0

摘要

通过 2-氰基-3-乙氧基丙烯酸乙酯与 N1,N3-二芳基丙二酰胺的反应，开发了一种合成以前未知的 2-氨基-1-(芳基)-5-(芳基氨基甲酰基)-6-氧代-1,6-二氢吡啶-3-羧酸乙酯的新方法。对一些合成化合物的抗菌活性进行了测定。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The synthesis of ethyl 2-amino-1-(aryl)-5-(arylcarbamoyl)-6-oxo-1,6-dihydropyridine-3-carboxylates

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The synthesis of ethyl 2-amino-1-(aryl)-5-(arylcarbamoyl)-6-oxo-1,6-dihydropyridine-3-carboxylates

A new method for the synthesis of previously unknown ethyl 2-amino-1-(aryl)-5-(arylcarbamoyl)-6-oxo-1,6-dihydropyridine-3-carboxylates by a reaction of ethyl 2-cyano-3-ethoxyacrylate with N¹,N³-diarylmalonamides was developed. The antibacterial activity of some of the synthesized compounds was assayed.

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来源期刊

Chemistry of Heterocyclic Compounds 化学-有机化学

CiteScore

2.90

自引率

13.30%

发文量

审稿时长

1 months

期刊介绍： The international journal Chemistry of Heterocyclic Compounds publishes original papers, short communications, reviews, and mini-reviews dealing with problems in the field of heterocyclic chemistry in Russian and English. The Journal also publishes reviews and annotations on new books and brief reports on conferences in the field of heterocyclic chemistry, as well as commemoratives dedicated to prominent heterocyclic chemists.