自体可扩张经导管瓣膜是治疗失败的小手术主动脉生物人工瓣膜的潜在有效选择。

IF 1.1 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Shohei Morita, Arudo Hiraoka, Genta Chikazawa, Shinya Takahashi, Taichi Sakaguchi, Hidenori Yoshitaka
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引用次数: 0

摘要

目的:经导管主动脉瓣植入失败的外科主动脉瓣生物假体已成为重新进行外科主动脉瓣置换术的高风险患者的替代选择。然而,经导管植入术后,衰竭外科主动脉瓣的大小与假体-患者不匹配发生率之间的相关性仍存在争议。本研究旨在分析和报告日本患者的结果:方法:回顾性研究了在我院接受经导管主动脉瓣植入术的 30 名患者,这些患者在手术主动脉瓣失效后接受了经导管主动脉瓣植入术,并提供了超声心动图和计算机断层扫描的结果:患者的平均年龄为(84.5 ± 4.8)岁。平均体表面积为 1.42 ± 0.13 平方米。根据失效生物假体的大小将患者分为两组:小型组(≦19 毫米)和大型组(> 19 毫米)。经导管植入 6 个月后,两组的平均压力梯度(12.2 ± 4.0 mmHg vs. 11.1 ± 1.2 mmHg; p = 0.54)和有效孔面积指数(1.00 ± 0.26 cm2/m2 vs. 0.99 ± 0.25 cm2/m2; p = 0.92)无明显差异。中度(38.5% 对 28.6%;p = 0.59)和重度(0% 对 7.1%;p = 0.33)假体与患者不匹配的发生率相当。两组患者的存活率无明显差异(对数秩检验 p 值 = 0.08):结论:在这批日本患者中,在衰竭的小主动脉瓣内进行经导管植入术并不会增加假体与患者不匹配的频率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Self-expandable transcatheter valve is a potentially useful option for a failing small surgical aortic bioprosthetic valve.

Self-expandable transcatheter valve is a potentially useful option for a failing small surgical aortic bioprosthetic valve.

Objective: Trans-catheter aortic valve implantation inside a failing surgical aortic valve bio-prosthesis has become an alternative for patients at high risk for redo surgical aortic valve replacement. However, the correlation between the size of the failing surgical aortic valve and the occurrence of prosthesis-patient mismatch after trans-catheter implantation is still controversial. The aim of this study is to analyze and report the results in Japanese patients.

Methods: Thirty patients who underwent trans-catheter aortic valve implantation inside a failing surgical aortic valve at our hospital were retrospectively reviewed with results from echocardiography and computed tomography.

Results: The patients' mean age was 84.5 ± 4.8 years. The mean body surface area was 1.42 ± 0.13 m2. The cohort was divided into two groups according to the size of the failing bio-prosthesis: small (≦19 mm) and large (> 19 mm). There were no significant differences in mean pressure gradient (12.2 ± 4.0 mmHg vs. 11.1 ± 1.2 mmHg; p = 0.54) and effective orifice area index (1.00 ± 0.26 cm2/m2 vs. 0.99 ± 0.25 cm2/m2; p = 0.92) between the groups at 6 months after trans-catheter implantation. The incidence of moderate (38.5% vs. 28.6%; p = 0.59) and severe (0% vs. 7.1%; p = 0.33) prosthesis-patient mismatch was equivalent. There was no significant difference in survival between the two groups (log-rank test p-value = 0.08).

Conclusions: Trans-catheter implantation inside a failing small aortic valve did not increase the frequency of prosthesis-patient mismatch in this Japanese cohort.

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来源期刊
General Thoracic and Cardiovascular Surgery
General Thoracic and Cardiovascular Surgery Medicine-Pulmonary and Respiratory Medicine
CiteScore
2.70
自引率
8.30%
发文量
142
期刊介绍: The General Thoracic and Cardiovascular Surgery is the official publication of The Japanese Association for Thoracic Surgery and The Japanese Association for Chest Surgery, the affiliated journal of The Japanese Society for Cardiovascular Surgery, that publishes clinical and experimental studies in fields related to thoracic and cardiovascular surgery.
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