叶黄素的保护特性:全面综述

Rasha Abdrabou, Rania Salama, Reem El-Naga, Samar Azab
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引用次数: 0

摘要

木犀草素是一种黄酮类化合物,在各种植物性食物中含量丰富,具有多方面的药理特征,具有广阔的治疗前景。这篇综述全面分析了木犀草素的药代动力学,阐明了它的吸收、分布、代谢和排泄特性。此外,还介绍了叶黄素的保护机制,包括其抗炎、抗氧化和抗细胞凋亡的特性,这些特性已在各种体外和体内模型中得到证实。此外,综述还探讨了叶黄素对心血管疾病、神经退行性疾病、癌症、肝脏和肾脏疾病等多种疾病的影响。此外,我们还讨论了木犀草素与传统化疗药物的协同作用,揭示了木犀草素在癌症治疗中的潜力。此外,我们还对正在进行的临床研究进行了深入探讨,强调需要进行更严格的调查,以验证叶黄素对人类的治疗效果。总之,木犀草素是一种很有前景的候选疗法,值得进一步研究,以充分挖掘其治疗潜力,促进其在各种疾病中的临床应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Protective Properties of Luteolin: A Comprehensive Review
Luteolin, a flavone abundant in various plant-based foods, presents a multifaceted pharmacological profile with promising therapeutic implications. This review provides a comprehensive analysis of the pharmacokinetics of luteolin, elucidating its absorption, distribution, metabolism, and excretion properties. Additionally, the protective mechanisms of luteolin are presented, encompassing its anti-inflammatory, antioxidant, and anti-apoptotic properties, which have been demonstrated in various in vitro and in vivo models. Furthermore, the review explores the impact of luteolin on diverse disorders, including cardiovascular diseases, neurodegenerative disorders, cancer, and liver and kidney diseases. In addition, the synergistic effects of luteolin with conventional chemotherapeutic agents are discussed, shedding light on its potential in cancer therapy. Furthermore, we provide insights into ongoing clinical studies, emphasizing the need for more rigorous investigation to validate the therapeutic benefits of luteolin in human populations. Overall, luteolin emerges as a promising therapeutic candidate, warranting further research to unlock its full therapeutic potential and facilitate its clinical application in various disease contexts.
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