布洛克-陶西格分流术在先天性心脏病患儿中的应用效果

Q4 Engineering
A. Kuchumov, A. Khairulin, A. Biyanov, A. Porodikov, Vagram Aratyunyan, Yuriy Sinelnikov
{"title":"布洛克-陶西格分流术在先天性心脏病患儿中的应用效果","authors":"A. Kuchumov, A. Khairulin, A. Biyanov, A. Porodikov, Vagram Aratyunyan, Yuriy Sinelnikov","doi":"10.15593/rjbiomech/2020.1.08","DOIUrl":null,"url":null,"abstract":"A problem of congenital heart defects with obstruction of the right ventricle output tract is urgent because of disease severity and need for multistage surgical treatment. The first stage of surgical correction is system–pulmonary shunt installation. Nevertheless, there are controversial views on the choice of the shunt optimal diameter and the implantation place selection. Anastomosis should provide sufficient, but no excessive pulmonary blood flow without reducing cardiac output, pulmonary vessels damage, and provide uniform growth of pulmonary arteries. In this paper, the model of blood flow in \"aorta–shunt–pulmonary artery\" is considered. A set of geometric images was obtained in four patients for the further import into ANSYS CFX finite element solver to solve the hemodynamic problem. Three variants of the modified Blalock–Taussig shunt installation were analyzed with by using widely adopted hemodynamic indices (wall shear stress, time averaged wall shear stress, oscillatory shear index, relative residence time). It was shown that shunting options differ for the various patients. Moreover, flow asymmetry in the pulmonary arteries at different implantation sites was noticed. Also, a comparison of hemodynamic performance was made to assess the effectiveness of the modified Blalock– Taussig shunt. An objectivized and personalized approach to specific treatment of each patient will significantly reduce child mortality and improve the quality of rehabilitation.","PeriodicalId":37840,"journal":{"name":"Russian Journal of Biomechanics","volume":" 28","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Effectiveness of Blalock–Taussig shunt performance in the congenital heart disease children\",\"authors\":\"A. Kuchumov, A. Khairulin, A. Biyanov, A. Porodikov, Vagram Aratyunyan, Yuriy Sinelnikov\",\"doi\":\"10.15593/rjbiomech/2020.1.08\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A problem of congenital heart defects with obstruction of the right ventricle output tract is urgent because of disease severity and need for multistage surgical treatment. The first stage of surgical correction is system–pulmonary shunt installation. Nevertheless, there are controversial views on the choice of the shunt optimal diameter and the implantation place selection. Anastomosis should provide sufficient, but no excessive pulmonary blood flow without reducing cardiac output, pulmonary vessels damage, and provide uniform growth of pulmonary arteries. In this paper, the model of blood flow in \\\"aorta–shunt–pulmonary artery\\\" is considered. A set of geometric images was obtained in four patients for the further import into ANSYS CFX finite element solver to solve the hemodynamic problem. Three variants of the modified Blalock–Taussig shunt installation were analyzed with by using widely adopted hemodynamic indices (wall shear stress, time averaged wall shear stress, oscillatory shear index, relative residence time). It was shown that shunting options differ for the various patients. Moreover, flow asymmetry in the pulmonary arteries at different implantation sites was noticed. Also, a comparison of hemodynamic performance was made to assess the effectiveness of the modified Blalock– Taussig shunt. An objectivized and personalized approach to specific treatment of each patient will significantly reduce child mortality and improve the quality of rehabilitation.\",\"PeriodicalId\":37840,\"journal\":{\"name\":\"Russian Journal of Biomechanics\",\"volume\":\" 28\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-03-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal of Biomechanics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15593/rjbiomech/2020.1.08\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Engineering\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Biomechanics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15593/rjbiomech/2020.1.08","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Engineering","Score":null,"Total":0}
引用次数: 3

摘要

先天性心脏缺陷合并右心室输出道梗阻的问题,由于病情严重,急需进行多阶段手术治疗。手术矫正的第一阶段是安装系统-肺分流管。然而,对于分流管最佳直径的选择和植入位置的选择还存在争议。吻合器应提供充足但不过量的肺血流,同时不降低心输出量、不损伤肺血管,并使肺动脉均匀生长。本文考虑了 "主动脉-分流-肺动脉 "的血流模型。本文获得了四名患者的一组几何图像,并将其进一步导入 ANSYS CFX 有限元求解器,以解决血流动力学问题。利用广泛采用的血液动力学指标(壁剪切应力、时间平均壁剪切应力、振荡剪切指数、相对停留时间)分析了改良布洛克-陶西格分流装置的三种变体。结果表明,不同患者的分流方案各不相同。此外,还发现不同植入部位的肺动脉血流不对称。此外,还对血液动力学表现进行了比较,以评估改良布洛克-陶西格分流术的有效性。针对每位患者的具体治疗采取客观化和个性化的方法,将大大降低儿童死亡率并提高康复质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effectiveness of Blalock–Taussig shunt performance in the congenital heart disease children
A problem of congenital heart defects with obstruction of the right ventricle output tract is urgent because of disease severity and need for multistage surgical treatment. The first stage of surgical correction is system–pulmonary shunt installation. Nevertheless, there are controversial views on the choice of the shunt optimal diameter and the implantation place selection. Anastomosis should provide sufficient, but no excessive pulmonary blood flow without reducing cardiac output, pulmonary vessels damage, and provide uniform growth of pulmonary arteries. In this paper, the model of blood flow in "aorta–shunt–pulmonary artery" is considered. A set of geometric images was obtained in four patients for the further import into ANSYS CFX finite element solver to solve the hemodynamic problem. Three variants of the modified Blalock–Taussig shunt installation were analyzed with by using widely adopted hemodynamic indices (wall shear stress, time averaged wall shear stress, oscillatory shear index, relative residence time). It was shown that shunting options differ for the various patients. Moreover, flow asymmetry in the pulmonary arteries at different implantation sites was noticed. Also, a comparison of hemodynamic performance was made to assess the effectiveness of the modified Blalock– Taussig shunt. An objectivized and personalized approach to specific treatment of each patient will significantly reduce child mortality and improve the quality of rehabilitation.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Russian Journal of Biomechanics
Russian Journal of Biomechanics Biochemistry, Genetics and Molecular Biology-Biophysics
CiteScore
1.10
自引率
0.00%
发文量
0
期刊介绍: Russian Journal of Biomechanics publishes peer reviewed articles related to the principal topics in biomechanics. This Journal was established to improve the information interchange between specialists on biomechanics from Russia and other countries. Biomechanics is defined as the mechanics of living tissues and biomaterials. The Journal presents original papers of a wide biomechanical profile. A balance of biomechanical and medical problems is the principal aspect of the Journal activities. The Journal encourages the submission of original articles, reviews, short communications and case studies in all areas of biomechanics, including, but not limited to: • General problems and methods of biomechanics • Rheological properties of living tissues • Biomaterials and prostheses • Dental biomechanics • Human movement analysis • Musculoskeletal biomechanics • Cardiovascular biomechanics • Biomechanics of breathing • Tissue and cellular biomechanics • Sport biomechanics • Biomechanical problems in biotechnology.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信