2018年在肯雅塔国立医院就诊的闭经和少经妇女中多囊卵巢综合征的流行率标准依据

F. Odera, J. Karanja, J. Kinuthia, O. Kireki, M. Kilonzo, A. Pulei, A. Kihara, M. Masinde, F. Odawa, R. Kosgei, O. Ogutu
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引用次数: 0

摘要

背景:多囊卵巢综合征(PCOS多囊卵巢综合征(PCOS)是导致女性无排卵性不孕的最常见内分泌疾病。在世界范围内,发病率差异很大,从 2.2% 到高达 26%。同样,多囊卵巢综合症在非洲的发病率也不尽相同,尼日利亚不孕妇女的发病率约为六分之一,坦桑尼亚不孕妇女的发病率为 32%。患病率不一的原因可能是诊断标准的多样性、与其他闭经综合征的表现形式相似以及所研究的人群。 研究目的根据标准确定2018年在肯雅塔国立医院就诊的闭经和少经妇女中多囊卵巢综合征的患病率。 方法:1:这是一项描述性横断面研究。研究人群包括在肯雅塔国立医院妇科招募的131名女性。入选者在知情同意的情况下填写了调查问卷,进行了人体测量,然后接受了盆腔超声波扫描,并抽取了血样检测血清游离睾酮水平。多囊卵巢综合症的判定标准包括 2003 年鹿特丹标准、1990 年美国国立卫生研究院标准和 2006 年 AE-PCOS 标准。 结果采用鹿特丹标准诊断出多囊卵巢综合症的有 49 人(37%),采用美国国立卫生研究院 1990 年标准诊断出多囊卵巢综合症的有 26 人(20%),采用 AE-PCOS 2006 年标准诊断出多囊卵巢综合症的有 15 人(12%)。 结论:采用鹿特丹标准时,发病率最高,其次是 NIH 1990 标准,最后是 AE-PCOS 2006 标准。 建议采用应使用鹿特丹标准诊断多囊卵巢综合症,因为它更具代表性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
PREVALENCE BY CRITERION BASIS FOR POLYCYSTIC OVARY SYNDROME AMONG WOMEN PRESENTING WITH AMENORRHEA AND OLIGOMENORRHEA AT THE KENYATTA NATIONAL HOSPITAL IN 2018
Background: Polycystic ovary syndrome (PCOS) is the commonest endocrinological condition associated  with anovulatory infertility in women. Worldwide, the prevalence is highly variable, ranging from 2.2% to  as high as 26%. Similarly, the prevalence of PCOS is variable in Africa, occurring in about 1 in 6 infertile  Nigerian women and 32% of infertile women in Tanzania. The variable prevalence could be attributable  to multiplicity of diagnostic criteria, and similarity in presentation with other syndromes that present with  amenorrhea and the population studied.  Objectives: To determine the prevalence by criterion basis of PCOS among women with amenorrhea and  oligomenorrhea attending the Kenyatta National Hospital in 2018.  Methodology: This was a descriptive cross sectional study. The study population comprised of 131 women  recruited at Kenyatta National Hospital gynecology department. Those enrolled, gave an informed consent,  filled a questionnaire, had their anthropometric measurements taken, then underwent a pelvic ultrasound scan  and a blood sample for serum free testosterone levels was taken. PCOS was determined using the Rotterdam  2003, the NIH 1990 and the AE-PCOS 2006 criteria.  Results: PCOS was diagnosed in 49(37%) using the Rotterdam criteria, 26(20%) using the NIH 1990 criteria  and 15(12%) using the AE-PCOS 2006 criteria.   Conclusion: When the Rotterdam criteria is used, the prevalence is highest, followed by the NIH 1990 and  lastly the AE-PCOS 2006.  Recommendation: The Rotterdam criteria for diagnosis of PCOS should be used as it more representative. 
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