肝细胞癌治疗的现代原则

Х Айвазян, З ИкрамовР., Ю Степанова, Б ВараваА., Минздрава России, Большая Серпуховская, Российская Федерация, Сеченова Минздрава России, Большая Сухаревская пл, A. VishnevskyV., Stepanova Yu, Kovalenko Yu, Zharikov Yu, Pakhomova A. Yu
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引用次数: 0

摘要

目的根据治疗结果分析,改善肝细胞癌患者的治疗效果、质量和预期寿命、预后。对 114 名肝细胞癌患者 2015-2020 年的长期治疗结果进行了分析。将患者分为两组:41例(35.9%)患者被纳入I组(R0手术可能切除的肿瘤),63例(55.2%)患者被纳入II组(晚期肿瘤不建议R0切除)。R0手术患者(48例)的精算生存率为:1年-85%,3年-65%,5年-55%;经动脉化疗栓塞术后肿瘤无法切除的患者的精算生存率为:1年-65%,3年-65%,5年-55%:1年--65%,3年--29%,5年--11%;采用局部破坏方法后--0.5年--75%,1年--36%,1.5年--22%。肝细胞癌患者的治疗结果证实了合理的多学科方法的可行性和有效性。这使得多学科医院能够取得令人满意的疗效。结果与大型外科中心的数据一致。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Modern principles of hepatocellular carcinoma treatment
Aim. To improve the treatment outcomes, quality and life expectancy, prognosis in patients with hepatocellular carcinoma based on an analysis of treatment outcomes.Materials and methods. The analysis of the long-term results of treatment of 114 patients with hepatocellular carcinoma for 2015–2020 was carried out. Two groups of patients were distinguished: 41 (35.9%) patients were included in group I (a potentially resectable tumor with R0 surgery), and 63 (55.2%) patients were included in group II (advanced tumor does not suggest R0 resection).Results. Actuarial survival for patients with R0 surgery (48) was: 1 year – 85%, 3 years – 65%, 5 years – 55%; in patients with unresectable tumor after transarterial chemoembolization: 1 year – 65%, 3 years – 29%, 5 years – 11%; after local destruction methods – 0.5 years – 75%, 1 year – 36%, 1.5 years – 22%.Conclusions. The results of treatment of patients with hepatocellular carcinoma confirm the feasibility and effectiveness of a rational multidisciplinary approach. It allows you to achieve satisfactory results in multidisciplinary hospitals. The results are consistent with the data of large surgical centers.
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