{"title":"用于磁共振弹性成像中组织弹性重构的物理信息神经网络","authors":"Matthew Ragoza, Kayhan Batmanghelich","doi":"10.1007/978-3-031-43999-5_32","DOIUrl":null,"url":null,"abstract":"<p><p>Magnetic resonance elastography (MRE) is a medical imaging modality that non-invasively quantifies tissue stiffness (elasticity) and is commonly used for diagnosing liver fibrosis. Constructing an elasticity map of tissue requires solving an inverse problem involving a partial differential equation (PDE). Current numerical techniques to solve the inverse problem are noise-sensitive and require explicit specification of physical relationships. In this work, we apply physics-informed neural networks to solve the inverse problem of tissue elasticity reconstruction. Our method does not rely on numerical differentiation and can be extended to learn relevant correlations from anatomical images while respecting physical constraints. We evaluate our approach on simulated data and <i>in vivo</i> data from a cohort of patients with non-alcoholic fatty liver disease (NAFLD). Compared to numerical baselines, our method is more robust to noise and more accurate on realistic data, and its performance is further enhanced by incorporating anatomical information.</p>","PeriodicalId":94280,"journal":{"name":"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11141115/pdf/","citationCount":"0","resultStr":"{\"title\":\"Physics-Informed Neural Networks for Tissue Elasticity Reconstruction in Magnetic Resonance Elastography.\",\"authors\":\"Matthew Ragoza, Kayhan Batmanghelich\",\"doi\":\"10.1007/978-3-031-43999-5_32\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Magnetic resonance elastography (MRE) is a medical imaging modality that non-invasively quantifies tissue stiffness (elasticity) and is commonly used for diagnosing liver fibrosis. Constructing an elasticity map of tissue requires solving an inverse problem involving a partial differential equation (PDE). Current numerical techniques to solve the inverse problem are noise-sensitive and require explicit specification of physical relationships. In this work, we apply physics-informed neural networks to solve the inverse problem of tissue elasticity reconstruction. Our method does not rely on numerical differentiation and can be extended to learn relevant correlations from anatomical images while respecting physical constraints. We evaluate our approach on simulated data and <i>in vivo</i> data from a cohort of patients with non-alcoholic fatty liver disease (NAFLD). Compared to numerical baselines, our method is more robust to noise and more accurate on realistic data, and its performance is further enhanced by incorporating anatomical information.</p>\",\"PeriodicalId\":94280,\"journal\":{\"name\":\"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11141115/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/978-3-031-43999-5_32\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/978-3-031-43999-5_32","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Physics-Informed Neural Networks for Tissue Elasticity Reconstruction in Magnetic Resonance Elastography.
Magnetic resonance elastography (MRE) is a medical imaging modality that non-invasively quantifies tissue stiffness (elasticity) and is commonly used for diagnosing liver fibrosis. Constructing an elasticity map of tissue requires solving an inverse problem involving a partial differential equation (PDE). Current numerical techniques to solve the inverse problem are noise-sensitive and require explicit specification of physical relationships. In this work, we apply physics-informed neural networks to solve the inverse problem of tissue elasticity reconstruction. Our method does not rely on numerical differentiation and can be extended to learn relevant correlations from anatomical images while respecting physical constraints. We evaluate our approach on simulated data and in vivo data from a cohort of patients with non-alcoholic fatty liver disease (NAFLD). Compared to numerical baselines, our method is more robust to noise and more accurate on realistic data, and its performance is further enhanced by incorporating anatomical information.