麻风坏死性结节性红斑:非典型严重 2 型麻风反应病例报告和文献综述。

Le infezioni in medicina Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI:10.53854/liim-3202-13
Alessandro Alfieri, Shinta Trilaksmi Dewi, Agnes Sri Siswati, Satiti Retno Pudjiati, Hardyanto Soebono
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引用次数: 0

摘要

迄今为止,麻风病仍是世界上的一个难题和挑战,因为麻风病会导致患者残疾和发病,包括因出现 2 型麻风反应或麻风结节性红斑(ENL)而引起的问题。ENL的临床表现可表现为非典型和严重的形式,称为ENL necroticans(ENN),这成为诊断和治疗中的一个难题。我们报告了一名患有麻风病和ENN的17岁女性患者,她接受了类固醇和甲氨蝶呤的联合治疗。接受治疗四个月后,患者身上的溃疡有所好转,但留下了萎缩性和增生性疤痕。ENN 的临床表现不寻常,给诊断带来了困难,因为它的外观不符合典型的模式,因此很难正确识别。此外,在处理 ENN 病例时,除了单纯使用类固醇外,可能还需要辅助治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Erythema nodosum leprosum necroticans: a case report of an atypical severe type 2 leprosy reaction and literature review.

Until now, leprosy remains a problem and challenge in the world because it can cause disability and morbidity in affected individuals, including problems due to the emergence of type 2 lepra reaction or erythema nodosum leprosum (ENL). The clinical picture of ENL can appear in an atypical and severe form, called ENL necroticans (ENN), which becomes a problem in diagnosis and therapy. We report a 17-year-old female with lepromatous leprosy and ENN who received therapy in the form of a combination of steroids and methotrexate. Four months after consuming this therapy, the ulcers on the patient's body improved, leaving atrophic and hypertrophic scars. ENN's unusual clinical presentation poses diagnostic difficulties in that its appearance does not follow the typical patterns, making it challenging to identify correctly. Furthermore, managing cases of ENN may necessitate supplementary treatment beyond steroids alone.

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