Arianna Bini, Prof. Mariella Mella, Prof. Daniele Merli, Prof. Stefano Protti
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Photochemical Vs Thermal Acid Catalysed Cyclization of Cannabigerol (CBG): An Unexpected Selectivity
The reactivity of Cannabigerol (CBG, 1) in organic solvents under photochemical and acid catalyzed conditions has been investigated in detail. The obtained results pointed out the presence of different reaction paths in the photochemical and the acid-catalyzed conditions, with a remarkable selectivity toward the formation of a 2,2-disubstituted-chromane derivative in the first case.