伯明翰髋关节置换术 25 年。

IF 4.9 1区 医学 Q1 ORTHOPEDICS
Rajpal S Nandra, Walid A Elnahal, Alistair Mayne, Lesley Brash, Callum W McBryde, Ronan B C Treacy
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引用次数: 0

摘要

目的:伯明翰髋关节置换术(BHR)于 1997 年推出,采用历史上久经考验的大直径金属对金属(MoM)轴承,以满足活跃的年轻患者的需求。以前曾有报道称,一名设计者外科医生连续为 130 名患者(144 个髋关节)进行了 5 年和 10 年的手术,分别有 3 次和 10 次失败。本研究的目的是将这一原始群组的随访时间延长至 25 年:本研究对所有适应症的 130 名患者的 144 例连续再植手术进行了延伸报告。所有手术均在 1997 年 8 月至 1998 年 5 月期间进行。手术时的平均年龄为52.1岁(SD 9.93;17至76岁),其中包括37名女性患者(28.5%)。失败的定义是因任何原因对其中一个组件进行翻修。进行了卡普兰-梅耶生存分析。对血清金属离子水平、X光片和牛津髋关节评分(OHS)进行了常规随访:结果:25岁时植入体的总存活率为83.50%(95%置信区间(CI)为0.79至0.90),有风险的人数为79人。男性患者 25 年的存活率为 89.5%(95% 置信区间为 0.83 至 0.96),而女性患者的存活率为 66.9%(95% 置信区间为 0.51 至 0.83)。在 10 到 25 年间,又有 10 例手术失败。其中四名患者出现了金属碎片不良反应,五名患者出现了股骨颈假体周围骨折,一名患者出现了无菌性松动。铬含量的中位数为 49.50 nmol/l(四分位距(IQR)为 34 至 70),钴含量的中位数为 42 nmol/l(四分位距(IQR)为 24.50 至 71.25)。最后一次随访的 OHS 中位数为 35(IQR 10 至 48)。在 25 年的研究期间,共有 29 名患者死亡。25年的患者存活率为75.10%(95% CI为0.67至0.83):这项研究表明,使用BHR的MoM髋关节置换术是全髋关节置换术(THA)的一种持久替代方案,尤其适用于希望保持高水平功能的年轻男性骨关节炎患者。这些结果优于全髋关节置换术的最佳结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Birmingham Hip Resurfacing at 25 years.

Aims: The Birmingham Hip Resurfacing (BHR) was introduced in 1997 to address the needs of young active patients using a historically proven large-diameter metal-on-metal (MoM) bearing. A single designer surgeon's consecutive series of 130 patients (144 hips) was previously reported at five and ten years, reporting three and ten failures, respectively. The aim of this study was to extend the follow-up of this original cohort at 25 years.

Methods: The study extends the reporting on the first consecutive 144 resurfacing procedures in 130 patients for all indications. All operations were undertaken between August 1997 and May 1998. The mean age at operation was 52.1 years (SD 9.93; 17 to 76), and included 37 female patients (28.5%). Failure was defined as revision of either component for any reason. Kaplan-Meier survival analysis was performed. Routine follow-up with serum metal ion levels, radiographs, and Oxford Hip Scores (OHSs) was undertaken.

Results: Overall implant survival was 83.50% (95% confidence interval (CI) 0.79 to 0.90) at 25 years, and the number at risk was 79. Survival in male patients at 25 years was 89.5% (95% CI 0.83 to 0.96) compared to 66.9% for female patients (95% CI 0.51 to 0.83). Ten additional failures occurred in the period of ten to 25 years. These involved an adverse reaction to metal debris in four patients, a periprosthetic femoral neck fracture affecting five patients, and aseptic loosening in one patient. The median chromium levels were 49.50 nmol/l (interquartile range (IQR) 34 to 70), and the median cobalt serum levels were 42 nmol/l (IQR 24.50 to 71.25). The median OHS at last follow-up was 35 (IQR 10 to 48). During the 25-year study period, 29 patients died. Patient survival at 25 years was 75.10% (95% CI 0.67 to 0.83).

Conclusion: This study demonstrates that MoM hip resurfacing using the BHR provides a durable alternative to total hip arthroplasty (THA), particularly in younger male patients with osteoarthritis wishing to maintain a high level of function. These results compare favourably to the best results for THAs.

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来源期刊
Bone & Joint Journal
Bone & Joint Journal ORTHOPEDICS-SURGERY
CiteScore
9.40
自引率
10.90%
发文量
318
期刊介绍: We welcome original articles from any part of the world. The papers are assessed by members of the Editorial Board and our international panel of expert reviewers, then either accepted for publication or rejected by the Editor. We receive over 2000 submissions each year and accept about 250 for publication, many after revisions recommended by the reviewers, editors or statistical advisers. A decision usually takes between six and eight weeks. Each paper is assessed by two reviewers with a special interest in the subject covered by the paper, and also by members of the editorial team. Controversial papers will be discussed at a full meeting of the Editorial Board. Publication is between four and six months after acceptance.
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