对桡骨远端环形骨折患儿进行软绷带包扎和立即出院与硬固定的成本效益分析。

IF 4.9 1区 医学 Q1 ORTHOPEDICS
Daniel C Perry, Melina Dritsaki, Juul Achten, Duncan Appelbe, Ruth Knight, James Widnall, Damian Roland, Shrouk Messahel, Matthew L Costa, James Mason
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引用次数: 0

摘要

目的:本试验旨在评估对桡骨远端环形骨折的 4-15 岁儿童进行软绷带包扎并立即出院与硬固定的成本效益:从英国国家医疗服务体系(NHS)和个人社会服务(PSS)的角度以及更广泛的社会角度进行了试验内经济评估。作为 "儿童前臂康复评估"(FORCE)多中心随机对照试验的一部分,我们利用试验病例报告表和患者填写的调查问卷,收集了为期六周的健康资源和生活质量(EQ-5D-Y)数据。对两个试验治疗组的成本和健康收益(质量调整生命年)进行了估算。使用回归法估算了新疗法在一系列 "支付意愿 "阈值下具有成本效益的概率,这些阈值反映了政府通常准备报销的每 QALY 成本范围:提供软绷带可显著降低每位患者的成本(节省 12.55 英镑(95% 置信区间(CI)-5.30 英镑至 19.80 英镑)),而 QALY 相近(组间 QALY 差异:0.0013(95% CI -0.0004 至 0.003))。在对一系列敏感性分析数据进行研究后发现,提供绷带是一种具有成本效益的选择的可能性很高(95%):除了已知的临床等效性之外,本研究还发现,在桡骨远端环形骨折患儿中,提供绷带与硬性固定相比可降低成本。虽然每位患者节省的费用较少,但此类损伤的高发率表明,整个医疗保健系统可节省大量费用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cost-effectiveness analysis of soft bandage and immediate discharge versus rigid immobilization in children with distal radius torus fractures.

Aims: The aim of this trial was to assess the cost-effectiveness of a soft bandage and immediate discharge, compared with rigid immobilization, in children aged four to 15 years with a torus fracture of the distal radius.

Methods: A within-trial economic evaluation was conducted from the UK NHS and personal social services (PSS) perspective, as well as a broader societal point of view. Health resources and quality of life (the youth version of the EuroQol five-dimension questionnaire (EQ-5D-Y)) data were collected, as part of the Forearm Recovery in Children Evaluation (FORCE) multicentre randomized controlled trial over a six-week period, using trial case report forms and patient-completed questionnaires. Costs and health gains (quality-adjusted life years (QALYs)) were estimated for the two trial treatment groups. Regression was used to estimate the probability of the new treatment being cost-effective at a range of 'willingness-to-pay' thresholds, which reflect a range of costs per QALY at which governments are typically prepared to reimburse for treatment.

Results: The offer of a soft bandage significantly reduced cost per patient (saving £12.55 (95% confidence interval (CI) -£5.30 to £19.80)) while QALYs were similar (QALY difference between groups: 0.0013 (95% CI -0.0004 to 0.003)). The high probability (95%) that offering a bandage is a cost-effective option was consistent when examining the data in a range of sensitivity analyses.

Conclusion: In addition to the known clinical equivalence, this study found that the offer of a bandage reduced cost compared with rigid immobilization among children with a torus fracture of the distal radius. While the cost saving was small for each patient, the high frequency of these injuries indicates a significant saving across the healthcare system.

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来源期刊
Bone & Joint Journal
Bone & Joint Journal ORTHOPEDICS-SURGERY
CiteScore
9.40
自引率
10.90%
发文量
318
期刊介绍: We welcome original articles from any part of the world. The papers are assessed by members of the Editorial Board and our international panel of expert reviewers, then either accepted for publication or rejected by the Editor. We receive over 2000 submissions each year and accept about 250 for publication, many after revisions recommended by the reviewers, editors or statistical advisers. A decision usually takes between six and eight weeks. Each paper is assessed by two reviewers with a special interest in the subject covered by the paper, and also by members of the editorial team. Controversial papers will be discussed at a full meeting of the Editorial Board. Publication is between four and six months after acceptance.
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