C J Welch, A Larsson, A C Ericson, B Oberg, R Datema, J Chattopadhyaya
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The chemical synthesis and antiviral properties of an acyclovir-phospholipid conjugate.
The synthesis of acyclovir-phospholipid conjugate (2) is reported through an unambiguous one-step preparation of L-alpha-dimyristoyl phosphatidic acid triethylammonium salt (5). The biological activity of 2 as an antiviral drug has also been investigated.
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