用于早期检测胰腺导管腺癌的成像技术：实施筛查和监测计划的最新进展和挑战。

IF 4.7 2区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

American Journal of Roentgenology Pub Date : 2024-08-01 Epub Date: 2024-05-29 DOI:10.2214/AJR.24.31151

Chenchan Huang, Elizabeth M Hecht, Erik V Soloff, Hina Arif Tiwari, Priya R Bhosale, Anil Dasayam, Samuel J Galgano, Avinash Kambadakone, Naveen M Kulkarni, Ott Le, Joy Liau, Lyndon Luk, Michael H Rosenthal, Guillermo P Sangster, Ajit H Goenka

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引用次数: 0

摘要

胰腺导管腺癌（PDA）是侵袭性最强的癌症之一。它的 5 年生存率仅为 12%，部分原因是大多数病例确诊时已是晚期，无法进行根治性手术切除。早期 PDA 的预后要好得多，因为治愈性干预的可能性增加，因此早期检测 PDA 对改善患者预后至关重要。我们研究了当前和不断发展的早期检测概念、筛查策略、高危人群的诊断率、争议以及标准护理成像的局限性。

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Imaging for Early Detection of Pancreatic Ductal Adenocarcinoma: Updates and Challenges in the Implementation of Screening and Surveillance Programs.

Pancreatic ductal adenocarcinoma (PDA) is one of the most aggressive cancers. It has a poor 5-year survival rate of 12%, partly because most cases are diagnosed at advanced stages, precluding curative surgical resection. Early-stage PDA has significantly better prognoses due to increased potential for curative interventions, making early detection of PDA critically important to improved patient outcomes. We examine current and evolving early detection concepts, screening strategies, diagnostic yields among high-risk individuals, controversies, and limitations of standard-of-care imaging.

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来源期刊

American Journal of Roentgenology 医学-核医学

CiteScore

12.80

自引率

4.00%

发文量

920

审稿时长

3 months

期刊介绍： Founded in 1907, the monthly American Journal of Roentgenology (AJR) is the world’s longest continuously published general radiology journal. AJR is recognized as among the specialty’s leading peer-reviewed journals and has a worldwide circulation of close to 25,000. The journal publishes clinically-oriented articles across all radiology subspecialties, seeking relevance to radiologists’ daily practice. The journal publishes hundreds of articles annually with a diverse range of formats, including original research, reviews, clinical perspectives, editorials, and other short reports. The journal engages its audience through a spectrum of social media and digital communication activities.