曲率校正系数,用于独立验证 Eclipse 中计算的电子处理计划的监控单元。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
ACS Applied Bio Materials Pub Date : 2024-09-01 Epub Date: 2024-05-28 DOI:10.1007/s13246-024-01421-0
Luke A Slama, Talat Mahmood, Brendan Mckernan
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引用次数: 0

摘要

电子束剂量测定对患者的表面轮廓很敏感。据文献报道,治疗计划系统(TPS)和独立监测单元(IMU)的计算结果相差超过 10%。在我们诊所,Radformation ClearCalc IMU 和 Eclipse TPS 电子蒙特卡罗(eMC)算法(v.16.1)之间也出现了类似的结果。本文介绍了在 3D 打印球形和圆柱形模型下测量的数据,以验证 eMC 算法在存在弯曲几何形状的情况下的有效性。测量使用了多个探测器,并与 Eclipse 中对 6、9 和 12 MeV 电子能量的计算结果进行了比较。这些数据被用来创建曲率校正因子(CCF),其定义为探测器读数与相同深度的曲面模型和平面模型之比。使用 NACP、Diode E、microSilicon 和 microDiamond 探测器计算的 TPS 和测量的 CCF 之间的平均差异分别为 1.3%、0.9%、0.7% 和 0.7%,最大差异分别为 4.5%、2.3%、1.9% 和 1.8%。将CCFs应用于先前失败患者的IMU计算,提高了与TPS的一致性。在 ESAPI 脚本的帮助下,我们诊所对特定患者的 IMU 计算实施了 CCF。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Curvature correction factors for the independent verification of monitor units of electron treatment plans calculated in Eclipse.

Curvature correction factors for the independent verification of monitor units of electron treatment plans calculated in Eclipse.

Electron beam dosimetry is sensitive to the surface contour of the patient. Over 10% difference between Treatment Planning System (TPS) and independent monitor-unit (IMU) calculations have been reported in the literature. Similar results were observed in our clinic between Radformation ClearCalc IMU and Eclipse TPS electron Monte Carlo (eMC) algorithm (v.16.1). This paper presents data measured under 3D printed spherical and cylindrical phantoms to validate the eMC algorithm in the presence of curved geometries. Measurements were performed with multiple detectors and compared to calculations made in Eclipse for the 6, 9 and 12 MeV electron energies. This data is used to create curvature correction factors (CCFs), defined as the ratio of the detector reading with the curved-surface phantom to a flat phantom at the same depth. The mean difference between the TPS calculated and measured CCFs using the NACP, Diode E, microSilicon, and microDiamond detectors were 1.3, 0.9, 0.7 and 0.7% respectively, with maximum differences of 4.5, 2.3, 1.9, and 1.8% respectively. Applying CCFs to previous failing patient IMU calculations improved agreement to the TPS. CCFs were implemented in our clinic for patient-specific IMU calculations with the assistance of a ESAPI script.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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