2004-2021 年德克萨斯州北美蝮蛇中毒后的筋膜切开术。

IF 3 3区 医学 Q2 TOXICOLOGY
Clinical Toxicology Pub Date : 2024-05-01 Epub Date: 2024-05-28 DOI:10.1080/15563650.2024.2338559
Shawn M Varney, Aaron A Alindogan, Haylea Stuteville, Brett A Roth, Sarah Watkins, Patrick C Ng, Han Tony Gao, Daniel L Dent, Joseph K Maddry
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引用次数: 0

摘要

简介:在美国,北美蝮蛇中毒每年发生 4,000 多起,多价法布抗蛇毒血清是主要治疗方法。由于担心蝮蛇椎间隙综合症,偶尔会对患者进行筋膜切开术。我们利用直接访问得克萨斯州毒物中心网络数据的机会,创建了一个新的蛇咬伤摘要表和数据库,其中包含 2004 年至 2021 年间的相关可用信息,并对得克萨斯州蝮蛇咬伤后筋膜切开术的发生率进行了识别、描述和估计:我们使用筋膜切开术、外科手术、腔室压力和腔室综合征等关键词搜索了德克萨斯州毒物中心网络数据库中 2004-2021 年间的病例。对数据进行了描述性统计:在 16,911 例报告的毒液中毒病例中,0.69% 涉及筋膜切开术(n = 117)。最常见的咬伤部位是指/手和下肢。接受筋膜切开术的患者通常为男性,年龄在 20-59 岁之间,比被蛇咬伤的总人数年轻 10 岁。在报告的腔室综合征病例中,只有 6% 的病例进行了腔室压力测量。101例(86.3%)病例注射了抗蛇毒血清,其中92例(91.1%)只注射了Fab抗蛇毒血清产品。大多数筋膜切开术与响尾蛇咬伤患者(47.9%)有关:讨论:我们的研究结果表明,被蛇咬伤的人数可能有所增加,但筋膜切开术却有所减少。总体而言,铜头蛇占蛇咬伤的大多数,但大多数筋膜切开术是响尾蛇咬伤所致(47.9%)。在这组病例中,筋膜室综合征的诊断和筋膜切开术的决定主要基于临床评估/外科医生的专业知识,而没有进行筋膜室压力测量。尽管抗蛇毒血清很有效,但在我们的研究中,只有 86.3% 的患者接受了抗蛇毒血清治疗:结论:在得克萨斯州,北美蝮蛇中毒后进行筋膜切开术的情况并不常见(0.69%),而且随着时间的推移有所减少,这可能是由于抗蛇毒血清的使用增加或外科医生对非手术治疗感到满意。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fasciotomy following North American pit viper envenomation in Texas 2004-2021.

Introduction: North American pit viper envenomation occurs over 4,000 times annually in the United States, with polyvalent Fab antivenom being the primary treatment. Fasciotomy is occasionally performed due to concerns about compartment syndrome. We utilized our direct access to Texas Poison Center Network data to create a new snakebite abstraction form and database on relevant available information between 2004 and 2021 and to identify, describe, and estimate the incidence of fasciotomy following pit viper envenomation in Texas.

Methods: We searched the Texas Poison Center Network database for cases during 2004-2021 using keywords such as fasciotomy, surgery, compartment pressure, and compartment syndrome. Descriptive statistics summarized the data.

Results: Of 16,911 reported envenomations, 0.69 percent involved fasciotomies (n = 117). Most common bite sites were digits/hands and lower extremities. Patients who underwent fasciotomy were typically male, aged 20-59, and 10 years younger than the total snakebite population. Only 6 percent of reported compartment syndrome cases had a compartment pressure measurement. Antivenom was administered in 101 (86.3 percent) cases, 92 (91.1 percent) of which received only Fab antivenom product. Patients with bites from rattlesnakes (47.9 percent) were associated with most fasciotomies.

Discussion: Our findings suggest a potential increase in snakebite exposures, accompanied by a decrease in fasciotomies. Overall, copperheads constituted the majority of snakebites, but most fasciotomies were from rattlesnake envenomations (47.9 percent). In this cohort, compartment syndrome diagnosis and decisions regarding fasciotomy were primarily based on clinical evaluation/surgeon expertise without compartment pressure measurements. Despite the efficacy of antivenom, only 86.3 percent of patients in our study received antivenom.

Conclusions: Fasciotomy after North American pit viper envenomation in Texas is uncommon (0.69 percent) and has decreased over time, possibly due to increased antivenom use or surgeon comfort with nonsurgical management.

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来源期刊
Clinical Toxicology
Clinical Toxicology 医学-毒理学
CiteScore
5.70
自引率
12.10%
发文量
148
审稿时长
4-8 weeks
期刊介绍: clinical Toxicology publishes peer-reviewed scientific research and clinical advances in clinical toxicology. The journal reflects the professional concerns and best scientific judgment of its sponsors, the American Academy of Clinical Toxicology, the European Association of Poisons Centres and Clinical Toxicologists, the American Association of Poison Control Centers and the Asia Pacific Association of Medical Toxicology and, as such, is the leading international journal in the specialty.
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