在挪威第二大医院的两年时间里,潜在的器官捐献者。

IF 1.9 4区 医学 Q2 ANESTHESIOLOGY
Acta Anaesthesiologica Scandinavica Pub Date : 2024-09-01 Epub Date: 2024-05-27 DOI:10.1111/aas.14455
Gunhild Holmaas, Edle Hilton, Stein Foss, Gaute K Wathle, Reidar Kvåle
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引用次数: 0

摘要

背景:挪威西部是挪威每百万居民中实际死亡器官捐献者最少的地区。我们希望了解该地区最大的医院--豪克兰大学医院两年内潜在捐献者和捐献器官的总人数,并评估潜在捐献者在哪里以及为什么会流失:我们对 2018-19 年在豪科兰大学医院死亡的所有患者进行了评估。我们检查了符合脑死亡后器官捐献标准的重症监护患者是否成为捐献者,以及潜在捐献者流失的原因。我们还估算了循环死亡后的潜在捐献者人数。我们检查了从重症监护室转出的患者和从未入住重症监护室的患者是否有可能捐献器官。我们登记了地点、性别、年龄和可能的器官数量:结果:在 1453 例院内死亡病例中,有 20 例脑死亡患者成为实际捐献者。有一名脑死亡患者和另外两名潜在捐献者(其中一人已出院住进病床病房)未在重症监护病房接受评估。五名患者的亲属拒绝捐献。其中三人符合挪威 2021 年关于循环死亡后器官捐献者的标准。有 10 名潜在的脑死亡器官捐献者从未入住重症监护病房,而是死于神经科或神经外科病房。如果所有潜在的器官捐献者都能实现捐献,那么捐献者的数量将增加一倍。移植器官的数量增幅较小,因为每位捐献者使用的器官将从 3.50 个降至 2.90 个:与挪威其他地区相比,我们的研究无法解释本地区器官捐献者人数偏低的原因。如果所有潜在的捐献都得以实施,实际捐献者的数量将翻一番。在重症监护室外死亡的病人是额外捐献者的最大潜在来源,最大限度地增加了42%的捐献者人数,优质肝脏捐献者增加了44%,肾脏捐献者增加了18%。在循环死亡后进行器官捐献可使捐献者人数增加 15%,高质量肝脏和肾脏的数量增加 12%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Potential organ donors during two years at the second largest hospital in Norway.

Background: Western Norway has the lowest number of actual deceased organ donors per million inhabitants in Norway. We wished to find the total number of potential donors and donor organs during 2 years at Haukeland University Hospital, the largest hospital in the region, and evaluate where and why potential donors were lost.

Methods: We evaluated all patients who died at Haukeland University Hospital in 2018-19. We checked if intensive care patients, filling the criteria as organ donors after brain death, became donors, and the reasons why potential donors were lost. We also estimated the number of potential donors after circulatory death. We checked if patients transferred from the intensive care units and patients never admitted to intensive care were potential donors. Location, gender, age, and possible number of organs were registered.

Results: Of 1453 in-hospital deaths, 20 brain-dead patients became actual donors. One brain-dead and two other potential donors, one of them discharged to a bed ward, were not evaluated at the intensive care units. Relatives refused in five patients. Three fulfilled the Norwegian criteria from 2021 as organ donors after circulatory death. Ten potential donors after brain death were never admitted to intensive care and died on neurological or neurosurgical wards. If all potential organ donors were realised, the number of donors would double. The number of transplanted organs would increase less, as organs used per donor would drop from 3.50 to 2.90.

Conclusion: Our study cannot explain the low number of donors in our region compared with the rest of Norway. If all potential donations were implemented, the number of actual donors would double. Patients dying outside the intensive care units represent the largest potential source for extra donors, maximally increasing the number of donors by 42%, high-quality livers 44% and kidneys 18%. Introducing organ donation after circulatory death may increase the number of donors by 15% and the number of high-quality livers and kidneys by 12%.

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来源期刊
CiteScore
4.30
自引率
9.50%
发文量
157
审稿时长
3-8 weeks
期刊介绍: Acta Anaesthesiologica Scandinavica publishes papers on original work in the fields of anaesthesiology, intensive care, pain, emergency medicine, and subjects related to their basic sciences, on condition that they are contributed exclusively to this Journal. Case reports and short communications may be considered for publication if of particular interest; also letters to the Editor, especially if related to already published material. The editorial board is free to discuss the publication of reviews on current topics, the choice of which, however, is the prerogative of the board. Every effort will be made by the Editors and selected experts to expedite a critical review of manuscripts in order to ensure rapid publication of papers of a high scientific standard.
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