{"title":"急性下呼吸道感染儿童的血清锌水平","authors":"Ankit Singla, Manorama Devi Govada, Prakash Medatwal, B.S Sharma","doi":"10.36106/ijsr/6206116","DOIUrl":null,"url":null,"abstract":"Introduction Acute Lower Respiratory Tract Infection (ALRTI) is an important cause of morbidity and mortality in the developing world.\nDeciency of micronutrients such as zinc may increase the risk of ALRTI. The aim of this study was to estimate serum zinc levels in children of\nunder-5 year's of age admitted with acute lower respiratory tract infection and to compare with healthy controls. MethodsAcase control Study was\ncarried out in the Department of Pediatrics of National Institute of Medical Sciences & Research, Jaipur. 70 children with Acute Lower Respiratory\nTract Infections, and another 70 served as controls. Blood samples were collected for zinc estimation in both case and control groups. Results Of\nthe 70 cases, Demographic data was comparable amongst gender groups. Baseline clinical characteristics of cases and control group were\ncomparable. Amongst the cases, 54 were diagnosed as bronchiolitis and 16 as bronchopneumonia. The mean (± SD) zinc levels among the cases\nwas 90.8± 59 μg/dl and in the control group, it was 98.78±66.26 μg/dl which was statistically non-signicant (p = 0.4526). Zinc deciency was\nobserved to be signicantly associated with the severity of bronchiolitis (p=0.00001) and bronchopneumonia (p=0.011) and prolonged hospital\nstay (p= 0.017) as a consequence. Conclusion The results of our study revealed that there was no signicant difference in the zinc level between\nchildren having Acute Lower Respiratory Tract Infection and controls. Zinc deciency was signicantly associated with severity of pneumonia\n(bronchiolitis and bronchopneumonia). However to further validate we need to have good quality studies with larger sample size and proper\nfollow-up.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"26 12","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"SERUM ZINC LEVELS IN CHILDREN WITH ACUTE LOWER RESPIRATORY INFECTIONS\",\"authors\":\"Ankit Singla, Manorama Devi Govada, Prakash Medatwal, B.S Sharma\",\"doi\":\"10.36106/ijsr/6206116\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction Acute Lower Respiratory Tract Infection (ALRTI) is an important cause of morbidity and mortality in the developing world.\\nDeciency of micronutrients such as zinc may increase the risk of ALRTI. The aim of this study was to estimate serum zinc levels in children of\\nunder-5 year's of age admitted with acute lower respiratory tract infection and to compare with healthy controls. MethodsAcase control Study was\\ncarried out in the Department of Pediatrics of National Institute of Medical Sciences & Research, Jaipur. 70 children with Acute Lower Respiratory\\nTract Infections, and another 70 served as controls. Blood samples were collected for zinc estimation in both case and control groups. Results Of\\nthe 70 cases, Demographic data was comparable amongst gender groups. Baseline clinical characteristics of cases and control group were\\ncomparable. Amongst the cases, 54 were diagnosed as bronchiolitis and 16 as bronchopneumonia. The mean (± SD) zinc levels among the cases\\nwas 90.8± 59 μg/dl and in the control group, it was 98.78±66.26 μg/dl which was statistically non-signicant (p = 0.4526). Zinc deciency was\\nobserved to be signicantly associated with the severity of bronchiolitis (p=0.00001) and bronchopneumonia (p=0.011) and prolonged hospital\\nstay (p= 0.017) as a consequence. Conclusion The results of our study revealed that there was no signicant difference in the zinc level between\\nchildren having Acute Lower Respiratory Tract Infection and controls. Zinc deciency was signicantly associated with severity of pneumonia\\n(bronchiolitis and bronchopneumonia). However to further validate we need to have good quality studies with larger sample size and proper\\nfollow-up.\",\"PeriodicalId\":14358,\"journal\":{\"name\":\"International journal of scientific research\",\"volume\":\"26 12\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of scientific research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36106/ijsr/6206116\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of scientific research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36106/ijsr/6206116","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
SERUM ZINC LEVELS IN CHILDREN WITH ACUTE LOWER RESPIRATORY INFECTIONS
Introduction Acute Lower Respiratory Tract Infection (ALRTI) is an important cause of morbidity and mortality in the developing world.
Deciency of micronutrients such as zinc may increase the risk of ALRTI. The aim of this study was to estimate serum zinc levels in children of
under-5 year's of age admitted with acute lower respiratory tract infection and to compare with healthy controls. MethodsAcase control Study was
carried out in the Department of Pediatrics of National Institute of Medical Sciences & Research, Jaipur. 70 children with Acute Lower Respiratory
Tract Infections, and another 70 served as controls. Blood samples were collected for zinc estimation in both case and control groups. Results Of
the 70 cases, Demographic data was comparable amongst gender groups. Baseline clinical characteristics of cases and control group were
comparable. Amongst the cases, 54 were diagnosed as bronchiolitis and 16 as bronchopneumonia. The mean (± SD) zinc levels among the cases
was 90.8± 59 μg/dl and in the control group, it was 98.78±66.26 μg/dl which was statistically non-signicant (p = 0.4526). Zinc deciency was
observed to be signicantly associated with the severity of bronchiolitis (p=0.00001) and bronchopneumonia (p=0.011) and prolonged hospital
stay (p= 0.017) as a consequence. Conclusion The results of our study revealed that there was no signicant difference in the zinc level between
children having Acute Lower Respiratory Tract Infection and controls. Zinc deciency was signicantly associated with severity of pneumonia
(bronchiolitis and bronchopneumonia). However to further validate we need to have good quality studies with larger sample size and proper
follow-up.