臀部表皮包涵囊肿背景下发生的鳞状细胞癌 - 病例报告

Praharsha G S, Patil Virupaxagouda, Kailas C T
{"title":"臀部表皮包涵囊肿背景下发生的鳞状细胞癌 - 病例报告","authors":"Praharsha G S, Patil Virupaxagouda, Kailas C T","doi":"10.36106/ijsr/8109036","DOIUrl":null,"url":null,"abstract":"Background: Methods: Epidermal inclusion cysts are the most common cutaneous cysts, but malignant transformation in them is extremely rare.\nWe present a case of a 63-year-old female with a swelling in the right gluteal region with associated discharge that was resected based on the clinical\nimpression and cytology of an epidermal inclusion cyst. Histopathologic exam showed atypical cells with enlarged nuclei and prominent nucleoli\nwith brisk mitotic activity, and on IHC, these cells were positive for PanCK and P40 and negative for Sox10, conrming the diagnosis of Poorly\nDifferentiated Squamous Cell Carcinoma. There are 56 reported cases of SCC arising on a background Conclusion: of epidermal inclusion cysts in\nliterature. Although epidermal inclusion cysts are usually benign, excision is recommended for atypical cysts with high suspicion for malignancy.\nThey should be excised intact and should undergo histopathological examination to rule out incipient malignancy.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"21 6","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"SQUAMOUS CELL CARCINOMA ARISING ON A BACKGROUND OF EPIDERMAL INCLUSION CYST OVER THE GLUTEAL REGION – A CASE REPORT\",\"authors\":\"Praharsha G S, Patil Virupaxagouda, Kailas C T\",\"doi\":\"10.36106/ijsr/8109036\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Methods: Epidermal inclusion cysts are the most common cutaneous cysts, but malignant transformation in them is extremely rare.\\nWe present a case of a 63-year-old female with a swelling in the right gluteal region with associated discharge that was resected based on the clinical\\nimpression and cytology of an epidermal inclusion cyst. Histopathologic exam showed atypical cells with enlarged nuclei and prominent nucleoli\\nwith brisk mitotic activity, and on IHC, these cells were positive for PanCK and P40 and negative for Sox10, conrming the diagnosis of Poorly\\nDifferentiated Squamous Cell Carcinoma. There are 56 reported cases of SCC arising on a background Conclusion: of epidermal inclusion cysts in\\nliterature. Although epidermal inclusion cysts are usually benign, excision is recommended for atypical cysts with high suspicion for malignancy.\\nThey should be excised intact and should undergo histopathological examination to rule out incipient malignancy.\",\"PeriodicalId\":14358,\"journal\":{\"name\":\"International journal of scientific research\",\"volume\":\"21 6\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of scientific research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36106/ijsr/8109036\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of scientific research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36106/ijsr/8109036","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

背景:方法:表皮包涵体囊肿是最常见的皮肤囊肿,但其恶变却极为罕见。我们报告了一例63岁女性的病例,她的右臀部肿胀并伴有分泌物,根据临床表现和细胞学检查,她被切除了表皮包涵体囊肿。组织病理学检查显示,这些细胞核增大,核小体突出,有丝分裂活跃,为非典型细胞;IHC检查显示,这些细胞PanCK和P40阳性,Sox10阴性,诊断为低分化鳞状细胞癌(PoorlyDifferentiated Squamous Cell Carcinoma)。表皮包涵囊肿背景下产生的鳞状细胞癌在文献中有56例报道 结论:表皮包涵囊肿背景下产生的鳞状细胞癌在文献中有56例报道。虽然表皮包涵囊肿通常是良性的,但对于高度怀疑为恶性的不典型囊肿,建议进行切除术。应完整切除囊肿,并进行组织病理学检查,以排除初期恶性肿瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SQUAMOUS CELL CARCINOMA ARISING ON A BACKGROUND OF EPIDERMAL INCLUSION CYST OVER THE GLUTEAL REGION – A CASE REPORT
Background: Methods: Epidermal inclusion cysts are the most common cutaneous cysts, but malignant transformation in them is extremely rare. We present a case of a 63-year-old female with a swelling in the right gluteal region with associated discharge that was resected based on the clinical impression and cytology of an epidermal inclusion cyst. Histopathologic exam showed atypical cells with enlarged nuclei and prominent nucleoli with brisk mitotic activity, and on IHC, these cells were positive for PanCK and P40 and negative for Sox10, conrming the diagnosis of Poorly Differentiated Squamous Cell Carcinoma. There are 56 reported cases of SCC arising on a background Conclusion: of epidermal inclusion cysts in literature. Although epidermal inclusion cysts are usually benign, excision is recommended for atypical cysts with high suspicion for malignancy. They should be excised intact and should undergo histopathological examination to rule out incipient malignancy.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信