加尔各答一所医学院收治的心脏外科术后患者留置导管尖端的细菌学特征和抗生素图谱

Ananya Pal, Aritra Bhattacharya, Sampa Dutta Gupta, Sujit Adhikari
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引用次数: 0

摘要

中心静脉导管、动脉导管和导尿管尖端的微生物检测和抗生素敏感性对减少术后患者感染至关重要。目的是,了解中心静脉导管、动脉导管和导尿管尖端培养阳性的发生率,并确定微生物及其抗生素敏感性。男性参与者居多,21 至 40 岁年龄组受影响最大,而 CABG 是最常见的手术方式。将样本培养在血琼脂和麦康凯琼脂上,然后进行革兰氏染色和生化测试,以确定微生物c。从不同导管尖端分离出的致病细菌的发生率显示,革兰氏阴性杆菌多于革兰氏阳性菌。大肠埃希菌和鲍曼不动杆菌对米诺环素最敏感,对氨基糖苷类药物部分敏感,对其他抗生素主要耐药。肺炎克雷伯菌对复方新诺明最敏感,对氨基糖苷类药物部分敏感。铜绿假单胞菌(Pseudomonasaeruginosa)具有泛耐药性。MRSA 对利奈唑胺和庆大霉素敏感,粪肠球菌对万古霉素敏感,葡萄球菌对复方新诺明和利奈唑胺敏感。因此,抗生素图谱是选择抗生素以防止出现细菌耐药性的重要工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
BACTERIOLOGICAL PROFILE AND ANTIBIOGRAM OF INDWELLING CATHETER TIPS IN POST OPERATIVE CARDIAC SURGICAL PATIENTS ADMITTED AT A MEDICAL COLLEGE IN KOLKATA
Microbial testing and antibiotic sensitivity from central venous, arterial line and urinary catheter tips have a paramount importance in reduction of infection in post operative patients. Objectives were to nd out the incidence of culture positive tips of central venous catheter, arterial line catheter and urinary catheter, and to identify the microorganisms along with their antibiotic sensitivity. Male participants were the majority with 21 to 40 years age group to be maximum affected and CABG to be the most common procedure involved. Samples were plated on blood agar and MacConkey agar, followed by performing gram stain and biochemical tests for microbial identication. Incidence of causative bacteria isolated from different catheter tips revealed gram negative bacilli to be more than gram positive organisms. Escherichia coli and Acinetobacter baumannii complex showed maximum sensitivity to Minocycline and partial sensitivity to aminoglycosides with other antibiotics to be predominantly resistant. Klebsiella pneumoniae showed maximum sensitivity to cotrimoxazole and partial sensitivity to aminoglycosides. Pseudomonas aeruginosa was pan resistant. MRSA was sensitive to linezolid, gentamicin, enterococcus faecium to vancomycin and staphylococcus saprophyticus to cotrimoxazole and linezolid. Antibiogram is thus an important tool in choosing selected antibiotics in order to prevent emergent bacterial resistance.
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