{"title":"从西孟加拉邦一所医学院重症监护室收治的呼吸机相关肺炎患者中分离出的需氧菌的细菌学特征和抗生素图谱","authors":"Aritra Bhattacharya","doi":"10.36106/ijsr/0208326","DOIUrl":null,"url":null,"abstract":"Culture sensitivity of deep tracheal suction samples collected from intubated patients has paramount importance in getting a proper antibiogram\nwhich can prevent morbidity and mortality and reduce the duration of ICU stay of the patients. Objectives are to nd out the bacteriological prole\nof isolates from deep tracheal suction samples at zero hours and at 48 hours of intubation, along with their antibiotic sensitivity pattern. 51\nparticipants whose samples showed no growth at zero hours of intubation were included. Among the remaining 51 samples, 36 were found culture\npositive at 48 hours of intubation, where male participants were the majority with >60 years age group being maximally affected. Samples were\ncollected in ICU, sent immediately to the microbiology laboratory followed by direct gram staining, and after plating, incubation, motility test and\nvarious biochemical identication methods, ABST was performed. Incidence of causative bacteria revealed gram negative bacilli to be more than\ngram positive organisms. Klebsiella pneumoniae showed maximum sensitivity to amikacin with other drugs being partially sensitive.\nAcinetobacter baumannii complex showed maximum sensitivity to levooxacin and amikacin, while being completely resistant to all other drugs.\nAmikacin and piperacillin tazobactam served the best combination therapy against Pseudomonas aeruginosa, while MRSA showed maximum\nsensitivity to linezolid. Antibiogram is thus an important tool in choosing selected antibiotics in order to prevent emergence of bacterial resistance\nin ventilator patients.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"358 21","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"BACTERIOLOGICAL PROFILE AND ANTIBIOGRAM OF AEROBIC BACTERIA ISOLATED FROM PATIENTS WITH VENTILATOR ASSOCIATED PNEUMONIA ADMITTED IN CRITICAL CARE UNIT OF A MEDICAL COLLEGE IN WEST BENGAL\",\"authors\":\"Aritra Bhattacharya\",\"doi\":\"10.36106/ijsr/0208326\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Culture sensitivity of deep tracheal suction samples collected from intubated patients has paramount importance in getting a proper antibiogram\\nwhich can prevent morbidity and mortality and reduce the duration of ICU stay of the patients. Objectives are to nd out the bacteriological prole\\nof isolates from deep tracheal suction samples at zero hours and at 48 hours of intubation, along with their antibiotic sensitivity pattern. 51\\nparticipants whose samples showed no growth at zero hours of intubation were included. Among the remaining 51 samples, 36 were found culture\\npositive at 48 hours of intubation, where male participants were the majority with >60 years age group being maximally affected. Samples were\\ncollected in ICU, sent immediately to the microbiology laboratory followed by direct gram staining, and after plating, incubation, motility test and\\nvarious biochemical identication methods, ABST was performed. Incidence of causative bacteria revealed gram negative bacilli to be more than\\ngram positive organisms. Klebsiella pneumoniae showed maximum sensitivity to amikacin with other drugs being partially sensitive.\\nAcinetobacter baumannii complex showed maximum sensitivity to levooxacin and amikacin, while being completely resistant to all other drugs.\\nAmikacin and piperacillin tazobactam served the best combination therapy against Pseudomonas aeruginosa, while MRSA showed maximum\\nsensitivity to linezolid. Antibiogram is thus an important tool in choosing selected antibiotics in order to prevent emergence of bacterial resistance\\nin ventilator patients.\",\"PeriodicalId\":14358,\"journal\":{\"name\":\"International journal of scientific research\",\"volume\":\"358 21\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of scientific research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36106/ijsr/0208326\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of scientific research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36106/ijsr/0208326","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
BACTERIOLOGICAL PROFILE AND ANTIBIOGRAM OF AEROBIC BACTERIA ISOLATED FROM PATIENTS WITH VENTILATOR ASSOCIATED PNEUMONIA ADMITTED IN CRITICAL CARE UNIT OF A MEDICAL COLLEGE IN WEST BENGAL
Culture sensitivity of deep tracheal suction samples collected from intubated patients has paramount importance in getting a proper antibiogram
which can prevent morbidity and mortality and reduce the duration of ICU stay of the patients. Objectives are to nd out the bacteriological prole
of isolates from deep tracheal suction samples at zero hours and at 48 hours of intubation, along with their antibiotic sensitivity pattern. 51
participants whose samples showed no growth at zero hours of intubation were included. Among the remaining 51 samples, 36 were found culture
positive at 48 hours of intubation, where male participants were the majority with >60 years age group being maximally affected. Samples were
collected in ICU, sent immediately to the microbiology laboratory followed by direct gram staining, and after plating, incubation, motility test and
various biochemical identication methods, ABST was performed. Incidence of causative bacteria revealed gram negative bacilli to be more than
gram positive organisms. Klebsiella pneumoniae showed maximum sensitivity to amikacin with other drugs being partially sensitive.
Acinetobacter baumannii complex showed maximum sensitivity to levooxacin and amikacin, while being completely resistant to all other drugs.
Amikacin and piperacillin tazobactam served the best combination therapy against Pseudomonas aeruginosa, while MRSA showed maximum
sensitivity to linezolid. Antibiogram is thus an important tool in choosing selected antibiotics in order to prevent emergence of bacterial resistance
in ventilator patients.