利用背景知识发现临床路径中的拥堵动力学模型

IF 3.1 3区 计算机科学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
Francesco Lupia , Enrico Russo , Giacomo Longo , Andrea Pugliese
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引用次数: 0

摘要

临床路径(CP)由结构化的多学科指南和协议组成,用于模拟临床治疗步骤。应用 "临床路径 "的主要目的是优化疗效和效率--然而,"临床路径 "的实际实施可能很复杂,会导致重大偏差和意想不到的低效。在本文中,我们开发了一种利用流程挖掘技术和背景知识来识别和理解此类问题的方法。我们设计了特定的数据结构,旨在正确捕捉 CPs 实施过程中产生的数据,包括为单个患者治疗一种以上疾病的数据。然后,我们提供了一种发现和描述 CP 中拥塞动态的方法。由于由此产生的过程发现问题在理论上难以解决,我们开发了启发式算法,根据广泛的实验评估,证明该算法能够以合理的计算量发现有意义的知识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Discovering congestion dynamics models in clinical pathways using background knowledge

Clinical Pathways (CPs) consist of structured multidisciplinary guidelines and protocols used to model steps of clinical treatments. The main objective of applying CPs is that of optimizing both outcomes and efficiency — however, the actual implementation of CPs can be complex and result in important deviations and unexpected inefficiencies. In this paper, we develop an approach to identifying and understanding such problems by leveraging process mining techniques and background knowledge. We design specific data structures aimed at properly capturing the data produced during the implementation of CPs, including the treatment of more than one disease for a single patient. We then provide a methodology to discover and characterize congestion dynamics in CPs. Since the resulting process discovery problem is theoretically intractable, we develop heuristic algorithms that, based on an extensive experimental assessment, prove capable of discovering meaningful knowledge with a reasonable computational effort.

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来源期刊
Journal of Computational Science
Journal of Computational Science COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS-COMPUTER SCIENCE, THEORY & METHODS
CiteScore
5.50
自引率
3.00%
发文量
227
审稿时长
41 days
期刊介绍: Computational Science is a rapidly growing multi- and interdisciplinary field that uses advanced computing and data analysis to understand and solve complex problems. It has reached a level of predictive capability that now firmly complements the traditional pillars of experimentation and theory. The recent advances in experimental techniques such as detectors, on-line sensor networks and high-resolution imaging techniques, have opened up new windows into physical and biological processes at many levels of detail. The resulting data explosion allows for detailed data driven modeling and simulation. This new discipline in science combines computational thinking, modern computational methods, devices and collateral technologies to address problems far beyond the scope of traditional numerical methods. Computational science typically unifies three distinct elements: • Modeling, Algorithms and Simulations (e.g. numerical and non-numerical, discrete and continuous); • Software developed to solve science (e.g., biological, physical, and social), engineering, medicine, and humanities problems; • Computer and information science that develops and optimizes the advanced system hardware, software, networking, and data management components (e.g. problem solving environments).
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