Zoltán Szabó, Kitti Pankász, János Bozorádi, O. Hakkel, Szabolcs Bella, Bianka Fabinyi, Sandro Meucci, Péter Fürjes
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Microfluidic Cuvette for Near-Infrared Spectroscopy
: We intend to develop an in situ near-infrared spectroscopic solution for monitoring the nutrient composition (e.g., lactate concentration) in microfluidic channels of organ-on-chip devices. In this work, the effects of the geometry, surface quality, and architecture of the micro-volume cuvettes were characterized and optimized considering the signal-to-noise ratio and sensitivity of the proposed spectroscopic method in case of aqueous solutions. The applicability of the micro-volume near-infrared spectroscopy method using this specially designed microfluidic cuvette was proven.
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