半弓置换术中的 "脑优先 "全身逆行灌注和逆行脑灌注

Zhen Qin, Yannan Zhou, Bo Wang, Haohan Chen, Jiyue Xiong, Jun Gu
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引用次数: 0

摘要

研究目的本研究的目的是比较在中度低体温循环停滞(MHCA)条件下进行半弓置换手术时,脑先导全身逆行灌注(Bf-TBRP)与反向脑灌注(RCP)的早期疗效。方法我们分析了2020年1月1日至2022年7月31日期间在四川大学华西医院接受MHCA下Bf-TBRP(18例)或RCP(70例)半弓置换术的88例患者的数据。记录了院内死亡率、神经功能缺损和其他不良事件,并通过逻辑回归进行评估,以确定风险因素。结果Bf-TBRP组和RCP组在院内死亡率、心脏事件、神经功能缺损、透析、胃肠道并发症和瘫痪方面无明显差异(P > 0.05)。与 RCP 组相比,Bf-TBRP 组的住院时间明显缩短[Bf-TBRP:8 天(四分位数间距(IQR),7-10)vs RCP:10 天(IQR,8-13),p = 0.03],血小板输注次数明显减少[Bf-TBRP:1.0(IQR,0-1.0)vs RCP:1.0(IQR,1.0-2.0),p = 0.05]。在多变量逻辑回归分析中,急诊手术(p = 0.05)和手术持续时间(p = 0.03)被确定为风险因素。结论该研究表明,Bf-TBRP 是一种安全的技术,适用于接受 MHCA 半弓置换术的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
"Brain-First" Total Body Retrograde Perfusion and Retrograde Cerebral Perfusion in Hemi-Arch Replacement
Objective: The purpose of this study is to compare the early outcomes of brain-first total body retrograde perfusion (Bf-TBRP) in comparison with reverse cerebral perfusion (RCP) under moderate hypothermia circulatory arrest (MHCA) for hemi-arch replacement surgery. Methods: We analyzed the data of 88 patients who underwent hemi-arch replacement with Bf-TBRP (n = 18) or RCP (n = 70) under MHCA at West China Hospital of Sichuan University between 1 January 2020, and 31 July 2022. In-hospital mortality, neurological deficits, and other adverse events were recorded, which were evaluated with logistic regression to determine risk factors. Results: There was no significant difference between the Bf-TBRP and RCP groups in in-hospital mortality, cardiac events, neurological deficits, dialysis, gastrointestinal complications, and paralysis (p > 0.05). The Bf-TBRP group was associated with significantly shorter hospital stay [Bf-TBRP: 8 d (interquartile range (IQR), 7–10) vs. RCP: 10 d (IQR, 8–13), p = 0.03] and fewer platelet transfusions [Bf-TBRP: 1.0 (IQR, 0–1.0) vs. RCP: 1.0 (IQR, 1.0–2.0), p = 0.05] than the RCP group. On multivariable logistic regression analysis, emergency surgery (p = 0.05) and surgery duration (p = 0.03) were determined to be risk factors. Conclusions: The study showed that Bf-TBRP is a safe technique for patients undergoing hemi-arch replacement with MHCA.
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