The biology of reactivity in human relationships: a conversation with Victoria Harrison

The concept of differentiation of self and its relationship to the natural capacity of humans and other social animals to adapt underpins clinician and researcher Victoria Harrison's long-term investigation of the biology of reactivity in relationships. Victoria's early research related to infertility and reproduction demonstrated how reactivity in at least three prior generations can contribute to chronic conditions, such as endometriosis, that are less amenable to intervention. Her most recent project, the ‘Observations of Change in Physiology and Family’ research, highlights how work on differentiation of self improves functional outcomes in physical and mental health for the family. While an individual may not experience the ‘calm mind’ that is often the goal of conventional therapeutic intervention, a significant reduction in symptoms and an improvement in overall functioning and relatedness are outcomes. This occurred when participants focused on increasing person-to-person contact with extended family members, reducing their emotional reactivity to significant others in the important triangles of their life and family and maintaining intellectual activity, often described as curiosity, even while reacting.