作为抗氧化剂的金纳米粒子的合成与应用

B. A. Suliasih, Setia Budi, Haliza Katas
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引用次数: 0

摘要

自由基导致的非传染性疾病(NCD)和过早衰老,促使人们对寻找有效的抗氧化剂进行广泛研究。目前,天然和合成的抗氧化剂种类繁多,包括具有高抗氧化活性的金属纳米粒子。其中,金纳米粒子(AuNPs)因其毒性小、合成简单、可检测等优点而成为最受欢迎的抗氧化剂。AuNPs 的抗氧化特性增强了其在医疗保健领域的广泛应用潜力,包括用作抗衰老、抗炎、伤口愈合剂以及治疗各种疾病。本综述重点介绍了作为抗氧化剂的 AuNPs 的合成及其抗氧化能力评估方法的最新进展,并深入探讨了其作用机制和潜在的医疗应用。总之,考虑到 AuNPs 的物理化学和生物特性,以及未来发展的益处和潜在挑战,AuNPs 被认为是适合临床应用的前景广阔的有效抗氧化剂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Synthesis and application of gold nanoparticles as antioxidants
Non-communicable diseases (NCDs) and premature aging, caused by free radicals, have spurred a demand for extensive research into finding effective antioxidants. Currently, there is an abundance of both natural and synthetic antioxidants, including metal nanoparticles with high antioxidant activity. Among these, gold nanoparticles (AuNPs) stand out as favoured antioxidants because of their minimal toxicity, simple synthesis, and detectability. The antioxidant properties of AuNPs enhance its wide-ranging potential for use in healthcare including applications as anti-aging, anti-inflammatory, and wound healing agents, as well as treatment for various diseases. This review highlights recent progress in the synthesis of AuNPs as antioxidants and method for assessing their antioxidant capacity as well as delves into their mechanism of action and explores their potential health applications. In conclusion, considering the physicochemical and biological properties, along with the benefits and potential challenges for future development, AuNPs are deemed promising and effective antioxidants suitable for clinical applications.
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