P.029 脑静脉血栓的血管内治疗:一项国际调查

BA Brakel, A. Rebchuk, J. Ospel, M. Heran, M. Goyal, M. Hill, Z. Miao, Y Chen, S. Sacco, S. Yaghi, M. Ton, G. Thomalla, G. Boulouis, H. Yamagami, BC Campbell, J. Raymond, G. Saposnik, TN Nguyen, TS Field
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引用次数: 0

摘要

背景:脑静脉血栓(CVT)是中风的罕见病因,10%-15% 的患者会出现依赖性或死亡。血管内治疗(EVT)在治疗 CVT 中的作用仍存在争议,实践模式也不为人所知。方法:我们在 2023 年 5 月至 2023 年 10 月期间向全球的神经科医生、神经介入医生、神经外科医生和其他相关临床医生发放了一份包含 53 个问题的综合调查问卷。调查询问了有关 EVT 治疗 CVT 的实践模式和观点,并评估了有关未来临床试验的意见。调查结果显示61个国家的总回复率为31%(2744名受邀参与者中的863名回复者)。大多数人(74%)支持在某些 CVT 病例中使用 EVT。EVT的主要考虑因素包括意识水平恶化(86%)和其他临床缺陷(76%)。抽吸式机械血栓切除术(22%)和支架回取术(19%)是最常用的技术,但地区间存在差异。术后使用的抗凝剂主要是低分子量肝素(40%),但北美的受访者更倾向于使用非分叶肝素。大多数受访者支持未来进行 EVT 试验(90%)。结论:我们的调查显示,CVT 的 EVT 治疗方法存在明显的异质性,这凸显了进行充分有效的临床试验以指导标准护理实践的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
P.029 Endovascular therapy for cerebral venous thrombosis: an international survey
Background: Cerebral venous thrombosis (CVT) is a rare cause of stroke, with 10–15% of patients experiencing dependence or death. The role of endovascular therapy (EVT) in the management of CVT remains controversial and practice patterns are not well-known. Methods: We distributed a comprehensive 53-question survey to neurologists, neuro-interventionalists, neurosurgeons and other relevant clinicians globally from May 2023 to October 2023. The survey asked about practice patterns and perspectives on EVT for CVT and assessed opinions regarding future clinical trials. Results: The overall response rate was 31% (863 respondents from 2744 invited participants) across 61 countries. A majority (74%) supported use of EVT for certain CVT cases. Key considerations for EVT included worsening level of consciousness (86%) and other clinical deficits (76%). Mechanical thrombectomy with aspiration (22%) and stent retriever (19%) were the most utilized techniques, with regional variations. Post-procedurally, low molecular weight heparin was the predominant anticoagulant administered (40%), although North American respondents favored unfractionated heparin. Most respondents supported future trials of EVT (90%). Conclusions: Our survey reveals significant heterogeneity in approaches to EVT for CVT, highlighting the necessity for adequately powered clinical trials to guide standard-of-care practices.
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