[深部脑刺激治疗抽动症和神经精神疾病挑战]。

Q4 Medicine
Yuiko Kimura, Masaki Iwasaki
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引用次数: 0

摘要

脑深部刺激(DBS)治疗抽动症的疗效已得到广泛认可。在本文中,我们对 38 名患者进行了脑深部刺激术,证实其疗效与国际报道的疗效相当。虽然许多患者症状严重,但手术适应症仍存在争议。原因之一是图雷特综合征有可能自发缓解,而 DBS 治疗则需要长期管理,这对一些患者来说可能很困难。此外,虽然有报道称 DBS 有多个治疗目标,但尚未制定治疗指南。DBS 对强迫症、抑郁症和痴呆症等神经精神疾病的疗效正逐渐被报道出来。然而,这种疗法与妥瑞症的预期效果相似,存在许多局限性,因此在扩大这些疾病的适应症方面存在问题。这些疾病的适应症应与伦理问题一并处理。预计今后将收集到更多有关这一主题的数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Deep Brain Stimulation for Tourette's Syndrome and Challenging for Neuropsychiatric Disease].

The efficacy of deep brain stimulation(DBS)for Tourette's syndrome is being well established. Herein, we performed DBS in 38 patients and confirmed that its efficacy was comparable with that reported internationally. Although many patients experience severe symptoms, the indications for surgery remain controversial. One reason for this is that Tourette syndrome has the potential for spontaneous remission, while DBS treatment results in the need for long-term management, which can be difficult for some patients. Furthermore, while several targets for DBS have been reported, no treatment guidelines have yet been established. The efficacy of DBS for neuropsychiatric disorders, such as obsessive-compulsive disorder, depression, and dementia, is gradually being reported. However, this use has many limitations in terms of expectations similar to those seen with Tourette's syndrome, leading to problems with expanding indications for these disorders. Indications for these disorders should be addressed in conjunction with ethical issues. It is expected that more data on this topic will be collected in the future.

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来源期刊
Neurological Surgery
Neurological Surgery Medicine-Medicine (all)
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