丹麦首胎流产后精神障碍风险的重新分析。

IF 0.5 4区 医学 Q3 LAW
Issues in Law & Medicine Pub Date : 2024-01-01
David C Reardon
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引用次数: 0

摘要

背景:丹麦先前对首次人工流产后每月和每三个月首次接触精神病患者的比率进行了研究,结果显示,与首次活产相比,首次接触精神病患者的比率较高,但与人工流产前九个月的比率相似。因此,研究人员得出结论认为,人工流产对心理健康没有独立影响;人工流产后与分娩后的精神病接触率之间的任何差异完全归因于之前存在的心理健康差异。然而,这些结论与使用更长时间段的类似研究不一致。对已发表的丹麦数据进行稍长时间段的重新分析可能会调和这种不一致:方法:提取每月和每三个月的数据,重新分析堕胎后九个月和十二个月的累积效应:在所有精神病诊断中,与流产前 9 个月的比率相比,流产后 9 个月首次接触精神病患者的每月累积平均比率从几率比 1.12(95% CI:1.02 至 1.22)上升到流产后 12 个月的 1.49(95% CI:1.37 至 1.63)。在流产后 12 个月,首次接触精神病患者的比例在所有四个诊断分组中都较高,其中人格或行为障碍(OR=1.87;95% CI:1.48 至 2.36)和神经质、压力相关或躯体形式障碍(OR=1.60;95% CI:1.41 至 1.81)的比例最高:我们的重新分析表明,从至少九个月的观察期来看,丹麦的数据与大量基于记录和调查的研究结果一致。需要更长的观察期来捕捉周年反应和应对机制的衰竭,这可能会延迟对堕胎后影响的观察。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Reanalysis of Mental Disorders Risk Following First-Trimester Abortions in Denmark.

Background: A previous Danish study of monthly and tri-monthly rates of first-time psychiatric contact following first induced abortions reported higher rates compared to first live births but similar rates compared to nine months pre-abortion. Therefore, the researchers concluded abortion has no independent effect on mental health; any differences between psychiatric contacts after abortion and delivery are entirely attributable to pre-existing mental health differences. However, these conclusions are inconsistent with similar studies that used longer time frames. Reanalysis of the published Danish data over slightly longer time frames may reconcile this discordance.

Method: Monthly and tri-monthly data was extracted for reanalysis of cumulative effects over nine- and twelvemonths post-abortion.

Results: Across all psychiatric diagnoses, cumulative average monthly rate of first-time psychiatric contact increased from an odds ratio of 1.12 (95% CI: 1.02 to 1.22) at 9-months to 1.49 (95% CI: 1.37 to 1.63) at 12 months post-abortion as compared to the 9 months pre-abortion rate. At 12 months post-abortion, first-time psychiatric contact was higher across all four diagnostic groupings and highest for personality or behavioral disorders (OR=1.87; 95% CI:1.48 to 2.36) and neurotic, stress related, or somatoform disorders (OR=1.60; 95% CI: 1.41 to 1.81).

Conclusions: Our reanalysis revealed that the Danish data is consistent with the larger body of both record-based and survey- based studies when viewed over periods of observation of at least nine months. Longer periods of observation are necessary to capture both anniversary reactions and the exhaustion of coping mechanisms which may delay observation of post-abortion effects.

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来源期刊
Issues in Law & Medicine
Issues in Law & Medicine Medicine-Health Policy
CiteScore
0.70
自引率
0.00%
发文量
0
期刊介绍: Issues in Law & Medicine is a peer reviewed professional journal published semiannually. Founded in 1985, ILM is co-sponsored by the National Legal Center for the Medically Dependent & Disabled, Inc. and the Watson Bowes Research Institute. Issues is devoted to providing technical and informational assistance to attorneys, health care professionals, educators and administrators on legal, medical, and ethical issues arising from health care decisions. Its subscribers include law libraries, medical libraries, university libraries, court libraries, attorneys, physicians, university professors and other scholars, primarily in the U.S. and Canada, but also in Austria, Australia, Belgium, Brazil, Italy, The Netherlands, New Zealand, Japan, Russia, South Korea, Spain, Taiwan, and the United Kingdom.
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