预测非重度烧伤患者静息能量消耗的临床方程与间接热量计的并发有效性比较

Mr Tyler Osborne, Associate Professor Dale Edgar, Associate Professor Timothy Fairchild, Dr Brook Galna, Winthrop Professor Fiona Wood, Ms Brodie Allan, Mr Thomas Le Huray, Associate Professor Bradley Wall
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摘要

在接受烧伤治疗期间和治疗后,进食不足和进食过量都会抑制患者的恢复并对生活质量产生负面影响。临床医生需要准确估算静息能量消耗,以避免患者进食过多或过少。测量静息能量消耗的标准是间接热量计。许多烧伤治疗机构使用预测方程来制定喂食方案,因为这些方案比间接热量计更便宜、更省时、更方便,而且不需要专用设备。然而,这些临床方程在非严重烧伤(烧伤总面积小于 15%)中的有效性尚未得到证实。在这项研究中,我们使用七个临床方程对 35 名非严重烧伤患者的静息能量消耗进行了预测,并与标准(间接热量测定法)进行了比较。我们发现,所有临床方程在预测间接热量测定法测得的静息能量消耗时都可能不准确,其中肖菲尔德方程的吻合度最高(95% 的吻合度范围:-836 至 711 千卡/天-1)。即使校正了 TBSA,临床方程与间接热量测定法之间的一致性仍然很差。我们的研究结果表明,临床方程可能无法准确预测非严重烧伤患者的静息能量消耗。因此,我们呼吁在非重度烧伤后,不要仅仅依靠现有的预测方程来指导临床决定能量摄入。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
CONCURRENT VALIDITY OF CLINICAL EQUATIONS TO PREDICT RESTING ENERGY EXPENDITURE COMPARED TO INDIRECT CALORIMETRY IN NON-SEVERE BURN PATIENTS
Underfeeding and overfeeding can inhibit recovery and negatively impact quality of life during and after receiving treatment for a burn injury. Clinicians rely on accurate estimation of resting energy expenditure to avoid overfeeding or underfeeding their patients. The criterion standard for measuring resting energy expenditure is indirect calorimetry. Many burn services use predictive equations to prescribe feeding regimes because they are cheaper, time efficient and logistically more expedient than indirect calorimetry and do not require specialised equipment. However, the validity of these clinical equations has not been established in non-severe burns (<15% total burn surface area, TBSA). In this study, resting energy expenditure was predicted for 35 participants with non-severe burn injuries using seven clinical equations and compared with the criterion-standard (indirect calorimetry). We found that all clinical equations may be inaccurate in predicting resting energy expenditure measured using indirect calorimetry, with the Schofield equation agreeing most closely (95% limits of agreement: -836 to 711 kcal.day-1). Agreement between clinical equations and indirect calorimetry remained poor even after correcting for TBSA. Our findings indicate clinical equations may not accurately predict resting energy expenditure of people who have sustained a non-severe burn. As such, we urge caution against relying solely on the existing predictive equations to guide clinical decisions regarding energy intake after non-severe burns.
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