含有单磷脂 A 和 QS-21 的陆军脂质体制剂佐剂的 SARS-CoV-2 重组尖铁蛋白纳米颗粒疫苗：1 期随机、双盲、安慰剂对照、首次人体临床试验

{"title":"含有单磷脂 A 和 QS-21 的陆军脂质体制剂佐剂的 SARS-CoV-2 重组尖铁蛋白纳米颗粒疫苗：1 期随机、双盲、安慰剂对照、首次人体临床试验","authors":"Brittany L Ober Shepherd, Paul T Scott, Jack N Hutter, Christine Lee, Melanie D McCauley, Ivelese Guzman, Christopher Bryant, Sarah McGuire, Jessie Kennedy, Wei-Hung Chen, Agnes Hajduczki, T. Mdluli, Anais Valencia-Ruiz, M. Amare, G. Matyas, Mangala Rao, M. Rolland, J. Mascola, S. D. De Rosa, M. McElrath, David C. Montefiori, Leonid Serebryannyy, Adrian B McDermott, Sheila A Peel, Natalie D Collins, M. Joyce, M. Robb, Nelson L Michael, S. Vasan, K. Modjarrad, Beza Gebrehana, Melissa E. Greenleaf, Melinda J Hamer, Nathan K Jansen, Xiaotang Jing, Jael Kagai, Kamila Kourbanova, Michael A Koren, Monica L Martin, K. Wuertz, J. Regules, Aaron D Sanborn, David Wallace, Lei Zhu, Gregory D. Gromowski, Courtney Corbitt, Janice M Darden, V. Dussupt, Emily Golub, Jarrett A. Headley, Umair M Jarral, Jocelyn King, S. Krebs, Jenny Lay, Regina Lilly, Jennifer Lynch, Elizabeth J. Martinez, Sandra V. Mayer, Samantha McGeehon, Hyunna Lee, S. Schech, Mekdi Tadesse, Paul V Thomas, Yahel Romem, Erifile Zografos, Bob C Lin, S. ","doi":"10.1016/s2666-5247(23)00410-x","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":304166,"journal":{"name":"The Lancet Microbe","volume":"53 5","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"SARS-CoV-2 recombinant spike ferritin nanoparticle vaccine adjuvanted with Army Liposome Formulation containing monophosphoryl lipid A and QS-21: a phase 1, randomised, double-blind, placebo-controlled, first-in-human clinical trial\",\"authors\":\"Brittany L Ober Shepherd, Paul T Scott, Jack N Hutter, Christine Lee, Melanie D McCauley, Ivelese Guzman, Christopher Bryant, Sarah McGuire, Jessie Kennedy, Wei-Hung Chen, Agnes Hajduczki, T. Mdluli, Anais Valencia-Ruiz, M. Amare, G. Matyas, Mangala Rao, M. Rolland, J. Mascola, S. D. De Rosa, M. McElrath, David C. Montefiori, Leonid Serebryannyy, Adrian B McDermott, Sheila A Peel, Natalie D Collins, M. Joyce, M. Robb, Nelson L Michael, S. Vasan, K. Modjarrad, Beza Gebrehana, Melissa E. Greenleaf, Melinda J Hamer, Nathan K Jansen, Xiaotang Jing, Jael Kagai, Kamila Kourbanova, Michael A Koren, Monica L Martin, K. Wuertz, J. Regules, Aaron D Sanborn, David Wallace, Lei Zhu, Gregory D. Gromowski, Courtney Corbitt, Janice M Darden, V. Dussupt, Emily Golub, Jarrett A. Headley, Umair M Jarral, Jocelyn King, S. Krebs, Jenny Lay, Regina Lilly, Jennifer Lynch, Elizabeth J. Martinez, Sandra V. Mayer, Samantha McGeehon, Hyunna Lee, S. Schech, Mekdi Tadesse, Paul V Thomas, Yahel Romem, Erifile Zografos, Bob C Lin, S. \",\"doi\":\"10.1016/s2666-5247(23)00410-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":304166,\"journal\":{\"name\":\"The Lancet Microbe\",\"volume\":\"53 5\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Lancet Microbe\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/s2666-5247(23)00410-x\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Lancet Microbe","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/s2666-5247(23)00410-x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}