SMARTQC "微型 VFC"--一种简单的自制新工具,用于以可控方式进入视网膜下空间。

S. Boral, Shouvick Dan, Santanu Mitra
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摘要

开发一种简单的工具,用于清除保留在玻璃体下的 PFCL 气泡(R-PFCL),并在玻璃体下血肿(SMH)中的视网膜下间隙安全注射 rt-血浆蛋白原激活剂(rt-PA)。 我们进行了一项回顾性介入研究,开发了一种简单的自制微型 VFC,以可控方式进入视网膜下间隙。我们将 1 毫升注射器活塞的橡胶帽剪开,然后将剪开的活塞橡胶帽安装在空的 1 毫升结核菌素注射器内,并将其末端与玻璃体切割机的 VFC 管道相连。现在启动 VFC 模式,连接 38G/41G 视网膜下针头,以提取玻璃体下 PFCL 气泡(R-PFCL 组,n=12),并为重要的 SMH 病例注射 rt-PA(SMH 组,n=32)。对 BCVA、眼底照片和 OCT 进行分析。随访至少 6 个月。 R-PFCL组的视力从术前的平均BCVA LogMAR 0.99(20/195) ± 0.27提高到术后的平均BCVA LogMAR 0.75(20/112) ± 0.21(P值<0.05),SMH组的视力从术前的平均BCVA LogMAR 1.99(20/1954) ± 0.75提高到术后的平均BCVA LogMAR 0.75(20/112) ± 0.37(P值<0.001)。 我们自制的微型 VFC 是一种安全的工具,可用于提取保留在玻璃体下的 PFCL 气泡,并以可控的方式为视网膜下血肿输送精确剂量的视网膜下药物(如 rt-PA)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SMARTQC“Micro VFC" - A simple homemade new tool to access sub-retinal space in a controlled way.
To develop a simple tool to remove retained sub-macular PFCL bubbles (R-PFCL), and to inject rt- Plasminogen Activator(rt-PA) safely in sub-retinal space in sub-macular hematomas (SMH). A retrospective, interventional study was performed where we developed a simple homemade Micro-VFC to gain access to sub-retinal space in a controlled way. We cut the rubber cap of the plunger of a 1ml syringe and this cut rubber cap of the plunger was fitted inside an empty 1 ml tuberculin syringe and its end was fitted with the tubings of VFC of the vitrectomy machine. Now VFC mode was activated attaching a 38G/41G sub-retinal needle for extracting sub-macular PFCL bubbles (R-PFCL group, n=12) and to deliver rt-PA injection in significant SMH cases (SMH group, n=32). BCVA, fundus photograph and OCT were analysed. Follow-up was done for at least 6 months. Vision improved from preoperative mean BCVA LogMAR 0.99(20/195) ± 0.27 to post-operative mean BCVA LogMAR 0.75(20/112) ± 0.21 (p-value <0.05) in R-PFCL group and from preoperative mean BCVA LogMAR 1.99(20/1954) ± 0.75 to post-operative mean BCVA LogMAR 0.75(20/112) ± 0.37 (p-value <0.001) in SMH group. Our homemade Micro-VFC is a safe tool to extract retained sub-macular PFCL bubbles and to deliver a precise dose of sub-retinal drugs like rt-PA for a sub-retinal hematoma in a controlled way.
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