系索综合征延迟症状中的脱系效果研究

IF 0.3 Q4 SURGERY
H. Beniwal, N. P. K., Prakash Rao G., K. Srinivas, Krishnamurthy Talari, U. Nookathota
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引用次数: 0

摘要

导言 拴系脊髓综合征(TCS)是一种由拉伸引起的功能障碍,与脊髓尾部被无弹性组织拴系在硬脑膜上有关,限制了脊髓的活动。它不仅表现在儿童期,在成人期也很常见。在此,我们研究了脱系对延迟出现 TCS 的作用。材料与方法 纳入 2011 年 1 月至 2019 年 12 月期间所有有症状的 TCS 患者。术前通过 X 光、肾脏、输尿管和膀胱超声波检查、脊柱和大脑磁共振成像以及尿动力学检查进行评估。进行了脱系术,并切除了相关病理组织。使用秩方系统通过内克尔功能评分进行术前术后比较。结果 患者年龄在8至30岁之间,平均年龄为13.8岁。61.1%的病例最常见的症状是泌尿系统表现,其次是疼痛(41.6%)、感觉障碍(38.8%)、不对称乏力(30.5%)、骨科溃疡和营养性溃疡(各占22.2%)以及肠道异常(13.8%)。症状的平均持续时间为 5.52 年。71.4%的患者泌尿系统表现有所改善,80%的患者疼痛有所改善,71.4%的患者感觉功能障碍有所改善,80%的患者肠道功能障碍有所改善,90.9%的患者运动无力,100%的患者营养性溃疡有所改善。经比较,卡方值为 25.9993,P 值为 0.000032,差异显著(<0.05)。结论 早期脱系术效果良好。在我们的研究中,即使是延迟发病,脱系术也有显著的统计学改善。因此,作者建议,即使系带发现较晚并伴有明显功能障碍,也应通过脱系带手术进行干预。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Study of Outcome of Detethering in Delayed Presentation of Tethered Cord Syndrome
Introduction Tethered cord syndrome (TCS) is a stretch-induced functional disorder associated with tethering of caudal spinal cord to dura mater with inelastic tissue, limiting its movement. It not only manifests in childhood but also noted in adults. Here, we studied the role of detethering on delayed presentation of TCS. Material and Methods All patients of symptomatic TCS from January 2011 to December 2019 were included. Preoperative evaluation was done through X-ray; ultrasonography kidney, ureter, urinary bladder; magnetic resonance imaging spine and brain; and urodynamic studies. Detethering was done and associated pathology was excised. Preoperative and postoperative comparison was done through Necker functional score using chi-squared system. Results Age range was 8 to 30 years with mean age of 13.8 years. Most common presentation was urological manifestations in ∼61.1% of cases followed by pain in 41.6%, sensory deficits in 38.8%, asymmetric weakness in 30.5%, orthopaedic and trophic ulcers in 22.2% each, and bowel abnormalities in 13.8% of cases. Mean duration of symptoms was 5.52 years. Improvement in urological manifestations was in 71.4% patients, pain in 80%, sensory dysfunctions in 71.4%, bowel dysfunctions in 80%, motor weakness in 90.9%, and trophic ulcer in 100% patients. On comparison, chi-squared value was 25.9993 and p-value was 0.000032, which was significant (<0.05). Conclusion Detethering in early ages is already proven with good results. In our study, detethering showed statistically significant improvement even in delayed presentation. So, authors recommend to surgically interfere by detethering, even if tethering is detected late with significant deficits.
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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
52
审稿时长
12 weeks
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