阴道内涂抹 Palasha Udumbaradi 软膏对骨盆器官脱垂的影响

Krishna K. O, Maya Balakrishnan, Giby Thomas
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摘要

盆腔器官脱垂是指女性盆腔器官向下脱垂,这是由于通常固定盆腔器官位置的结构薄弱所致。盆腔器官脱垂的主要症状包括排尿障碍,如压力性尿失禁、排尿控制不佳、下坠感、姿势性腰痛、便秘和白带增多。盆腔器官脱垂的治疗包括预防性保守治疗和手术治疗。当保守治疗无效时,就需要进行手术治疗。不同的阿查里亚提到了三种不同的情况,如 Phalini、Prasramsini 和 Mahayoni vyapath,根据脱垂的阶段和部位来解释脱垂的情况。本研究采用了《Bhaishajya Ratnavali》中提到的 Palasha udumbaradi yoga,其中含有 Palasha beeja、Udumbara phala、Thilathaila 和 Madhu 等成分。Lepa 以药膏的改良形式使用。本研究试图评估 Palasha udumbaradi 软膏对子宫脱垂的影响。药膏经阴道内涂抹。阴道内有密集的血管,是局部和全身给药的潜在场所。与口服给药相比,阴道给药的主要优势在于可以避开恶劣的胃部环境,并绕过肝脏的首过代谢。一名 38 岁的妇女主诉排尿次数增多、压力性尿失禁、排尿灼热、腰痛和排尿困难,到特里普尼图拉政府阿育吠陀医学院门诊部就诊。患者自行在阴道内涂抹了 Palasha udumbaradi 软膏。建议连续使用 60 天,不包括月经期,并在第 90 天进行随访。第 0 天、第 30 天和第 60 天进行评估,第 90 天使用 POP-Q 量表、尿失禁量表和视觉模拟量表进行随访。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Intravaginal Application of Palasha Udumbaradi Ointment on Pelvic Organ Prolapse
Prolapse is a downward descent of the female pelvic organs as a result of weakness of the structures that normally retain them in position. The main symptoms of pelvic organ prolapse include micturition disturbances like stress incontinence, imperfect control of micturition, a feeling of lump coming down, postural low back ache, constipation and leucorrhoea. The management of pelvic organ prolapse includes preventive conservative and surgical measures. Surgery is indicated when conservative management fails. The three different conditions like Phalini, Prasramsini and Mahayoni vyapath mentioned by different Acharyas explain the prolapsed condition according to the stage and part prolapsed out. Palasha udumbaradi yoga mentioned in Bhaishajya Ratnavali containing ingredients such as Palasha beeja, Udumbara phala, Thilathaila and Madhu was taken for this study. The Lepa was applied in the modified form of an ointment. The study is an attempt to assess the effect of Palasha udumbaradi ointment on uterine prolapse. The ointment was applied intra vaginally. The presence of dense blood vasculature makes the vagina a potential site for local and systemic drug administration. The key advantages of vaginal drug delivery over oral administration is that this is able to circumvent the harsh gastric environment and also bypass hepatic first-pass metabolism. A 38 year woman with complaints of increased frequency of micturition, stress incontinence, burning micturition, low back ache and dyspareunia consulted the OPD of Govt. Ayurveda Medical College, Tripunithura. Palasha udumbaradi ointment was self-applied intra-vaginally. Administration of ointment was advised for 60 consecutive days excluding the days of menstruation with follow up on 90th day. Assessment was done on 0th, 30th and 60th day and follow up was done on 90th day using POP-Q Scale, urinary incontinence scale, and visual analogue scale.
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