A. Pak, Inst Med Sci, Shabana Abbas, M. Khattak, Sanober Hameed, Nouman Maqbool, Sami Saeed, Numan Majeed
{"title":"一家三甲医院意外发现因骨折就诊的老年患者肾功能异常","authors":"A. Pak, Inst Med Sci, Shabana Abbas, M. Khattak, Sanober Hameed, Nouman Maqbool, Sami Saeed, Numan Majeed","doi":"10.48036/apims.v20i2.905","DOIUrl":null,"url":null,"abstract":"Objective: To determine the incidental rate of renal impairment among elderly women with fractures who reported to the Orthopaedic OPD at a tertiary care Hospital.\nMethodology: This prospective cohort study was done at Orthopaedic department and OPD Fauji Foundation Hospital, Rawalpindi during a period of one year from March 2022 to February 2023. A total of 147 females aged >60 years presented with Hip fractures, surgically managed and who had history of normal pre-fracture renal function were included. A 5ml blood sample was obtained and sent to the Hospital diagnostic laboratory to evaluate the renal profile, serum calcium and vitamin D levels. All the information was recorded via pre-structured study proforma. \nResults: The study enrolled 147 elderly participants with an average age of 66.82 years. Among the participants, 24 patients (16.3%) experienced Acute Kidney Injury (AKI), with 9.5% having stage-I AKI, 4.8% with stage II AKI, and 2.0% with stage III AKI. Before sustaining the hip fracture, the mean serum creatinine level was 67.04 µmol/L, and following the fracture, it increased to 81.95 µmol/L (p-value < 0.0001). The severity of AKI did not exhibit a statistically significant correlation with the age of the patients. However, there was a statistically significant increase in serum creatinine levels among patients based on the duration of their fractures (p-value < 0.001).\nConclusion: The incidence of Acute Kidney Injury (AKI) in elderly patients following hip fractures was found to be 16.3%, with varying stages of severity.","PeriodicalId":184398,"journal":{"name":"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University","volume":"85 7","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Incidental Finding of Deranged Renal Function in Elderly Patients Presenting with Fractures in a Tertiary Care Hospital\",\"authors\":\"A. Pak, Inst Med Sci, Shabana Abbas, M. Khattak, Sanober Hameed, Nouman Maqbool, Sami Saeed, Numan Majeed\",\"doi\":\"10.48036/apims.v20i2.905\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: To determine the incidental rate of renal impairment among elderly women with fractures who reported to the Orthopaedic OPD at a tertiary care Hospital.\\nMethodology: This prospective cohort study was done at Orthopaedic department and OPD Fauji Foundation Hospital, Rawalpindi during a period of one year from March 2022 to February 2023. A total of 147 females aged >60 years presented with Hip fractures, surgically managed and who had history of normal pre-fracture renal function were included. A 5ml blood sample was obtained and sent to the Hospital diagnostic laboratory to evaluate the renal profile, serum calcium and vitamin D levels. All the information was recorded via pre-structured study proforma. \\nResults: The study enrolled 147 elderly participants with an average age of 66.82 years. Among the participants, 24 patients (16.3%) experienced Acute Kidney Injury (AKI), with 9.5% having stage-I AKI, 4.8% with stage II AKI, and 2.0% with stage III AKI. Before sustaining the hip fracture, the mean serum creatinine level was 67.04 µmol/L, and following the fracture, it increased to 81.95 µmol/L (p-value < 0.0001). The severity of AKI did not exhibit a statistically significant correlation with the age of the patients. However, there was a statistically significant increase in serum creatinine levels among patients based on the duration of their fractures (p-value < 0.001).\\nConclusion: The incidence of Acute Kidney Injury (AKI) in elderly patients following hip fractures was found to be 16.3%, with varying stages of severity.\",\"PeriodicalId\":184398,\"journal\":{\"name\":\"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University\",\"volume\":\"85 7\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.48036/apims.v20i2.905\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.48036/apims.v20i2.905","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的确定在一家三级医院骨科手术室就诊的骨折老年妇女中肾功能损害的偶发率:这项前瞻性队列研究于 2022 年 3 月至 2023 年 2 月在拉瓦尔品第市福吉基金会医院骨科和手术室进行,为期一年。共纳入了 147 名年龄大于 60 岁的髋部骨折女性患者,她们均接受过手术治疗,且骨折前肾功能正常。患者被抽取 5 毫升血液样本并送往医院诊断实验室,以评估肾功能、血清钙和维生素 D 水平。所有信息均通过预先设计好的研究表格进行记录。研究结果研究共纳入 147 名老年参与者,平均年龄为 66.82 岁。其中,24 名患者(16.3%)出现急性肾损伤(AKI),9.5% 为 AKI I 期,4.8% 为 AKI II 期,2.0% 为 AKI III 期。髋部骨折前,平均血清肌酐水平为 67.04 µmol/L,骨折后则升至 81.95 µmol/L(P 值 < 0.0001)。AKI 的严重程度与患者的年龄没有明显的统计学相关性。然而,根据骨折持续时间的长短,患者的血清肌酐水平有统计学意义的增加(p 值 < 0.001):结论:老年髋部骨折患者的急性肾损伤(AKI)发生率为16.3%,严重程度各不相同。
Incidental Finding of Deranged Renal Function in Elderly Patients Presenting with Fractures in a Tertiary Care Hospital
Objective: To determine the incidental rate of renal impairment among elderly women with fractures who reported to the Orthopaedic OPD at a tertiary care Hospital.
Methodology: This prospective cohort study was done at Orthopaedic department and OPD Fauji Foundation Hospital, Rawalpindi during a period of one year from March 2022 to February 2023. A total of 147 females aged >60 years presented with Hip fractures, surgically managed and who had history of normal pre-fracture renal function were included. A 5ml blood sample was obtained and sent to the Hospital diagnostic laboratory to evaluate the renal profile, serum calcium and vitamin D levels. All the information was recorded via pre-structured study proforma.
Results: The study enrolled 147 elderly participants with an average age of 66.82 years. Among the participants, 24 patients (16.3%) experienced Acute Kidney Injury (AKI), with 9.5% having stage-I AKI, 4.8% with stage II AKI, and 2.0% with stage III AKI. Before sustaining the hip fracture, the mean serum creatinine level was 67.04 µmol/L, and following the fracture, it increased to 81.95 µmol/L (p-value < 0.0001). The severity of AKI did not exhibit a statistically significant correlation with the age of the patients. However, there was a statistically significant increase in serum creatinine levels among patients based on the duration of their fractures (p-value < 0.001).
Conclusion: The incidence of Acute Kidney Injury (AKI) in elderly patients following hip fractures was found to be 16.3%, with varying stages of severity.