Knowledge about Administration and Regulation of High Alert Medication among Nurses in Oncology Department

Background: High alert medications (HAMs) are associated with a higher risk of causing significant patient harm when used in error. Understanding the administration and regulation of these medications within oncology settings is critical due to the complex nature of cancer treatment regimens and the severity of potential medication errors. Objective: To assess the knowledge of nurses regarding the administration and regulation of high alert medications in an oncology department of a tertiary care hospital. Methods: A descriptive cross-sectional study was conducted among 133 registered nurses in the oncology department of Jinnah Hospital, Lahore. Data were collected using a structured questionnaire designed to evaluate nurses' knowledge of HAMs. Participants included both male (29.3%) and female (70.7%) nurses, with varying educational backgrounds and work experiences. Statistical analysis was performed using SPSS version 25, focusing on descriptive statistics such as frequencies, percentages, means, and standard deviations. Results: The results revealed moderate knowledge levels among nurses with significant gaps in critical areas. Only 20.3% correctly identified the protocol for fast IV push of 1:1000 epinephrine in mild allergic reactions, and 33.8% mistakenly believed that 10% calcium gluconate and 10% calcium chloride were interchangeable. Additionally, 44.4% incorrectly used 'Amp' or 'Vial' for dose expression instead of 'mg' or 'gm', and 53.4% failed to recognize the importance of distinctive labeling on look-alike drugs. Conclusion: The study highlights the need for enhanced educational programs and standardized protocols to improve the safe administration and regulation of HAMs in oncology settings. Strengthening nurses' knowledge and practices regarding HAMs is essential to reduce medication errors and improve patient outcomes.