通过二阶灵敏度矩阵进行荧光分子断层重构的方法

IF 1.9 4区物理与天体物理 Q3 OPTICS

Journal of the European Optical Society-Rapid Publications Pub Date : 2024-05-07 DOI:10.1051/jeos/2024025

W. Zou

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引用次数: 0

摘要

荧光分子断层成像（FMT）重建通常基于雅各布矩阵求解，而雅各布矩阵是一阶灵敏度矩阵。基本上，使用二阶导数进行迭代重建有助于提高收敛性能。本文提出了一种基于减少二阶灵敏度矩阵的 FMT 重建方法。此外，在逆重建中结合了探测器旋转的策略，进一步提高了重建质量。重建结果表明，本文提出的方法能加快重建速度，并获得高精度的逆解。

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A method of fluorescence molecular tomographic reconstruction via the second-order sensitivity matrix

Fluorescence molecular tomographic (FMT) reconstruction is commonly solved based on the Jacobian matrix, which is a first-order sensitivity matrix. Basically, using the second-order derivatives for iterative reconstruction can help improve the performance of convergence. In this paper, a reconstruction method of FMT based on the reduction of the second-order sensitivity matrix is proposed. In addition, the strategy of detectors rotation is combined into the inverse reconstruction to further improve the reconstruction quality. The reconstructed results demonstrate that the proposed method accelerates the reconstruction with high precision of inverse solutions.

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来源期刊

Journal of the European Optical Society-Rapid Publications 物理-光学

CiteScore

2.40

自引率

0.00%

发文量

审稿时长

5 weeks

期刊介绍： Rapid progress in optics and photonics has broadened its application enormously into many branches, including information and communication technology, security, sensing, bio- and medical sciences, healthcare and chemistry. Recent achievements in other sciences have allowed continual discovery of new natural mysteries and formulation of challenging goals for optics that require further development of modern concepts and running fundamental research. The Journal of the European Optical Society – Rapid Publications (JEOS:RP) aims to tackle all of the aforementioned points in the form of prompt, scientific, high-quality communications that report on the latest findings. It presents emerging technologies and outlining strategic goals in optics and photonics. The journal covers both fundamental and applied topics, including but not limited to: Classical and quantum optics Light/matter interaction Optical communication Micro- and nanooptics Nonlinear optical phenomena Optical materials Optical metrology Optical spectroscopy Colour research Nano and metamaterials Modern photonics technology Optical engineering, design and instrumentation Optical applications in bio-physics and medicine Interdisciplinary fields using photonics, such as in energy, climate change and cultural heritage The journal aims to provide readers with recent and important achievements in optics/photonics and, as its name suggests, it strives for the shortest possible publication time.