微型/纳米流体芯片的最新进展以及在癌症研究和治疗中的应用

Yixuan Li
{"title":"微型/纳米流体芯片的最新进展以及在癌症研究和治疗中的应用","authors":"Yixuan Li","doi":"10.54254/2755-2721/61/20240916","DOIUrl":null,"url":null,"abstract":"Micro/nanofluidic chips have set a new stage for cancer research and therapy, revolutionising the way we detect, diagnose, and treat this formidable disease. This paper provides an overview of the basic properties of micro/nanofluidic chips and current progress in the utilization of micro/nanofluidic chips in the realm of cancer. Their application in DNA and protein analysis, their role in cancer modelling and drug testing, and their innovative use in drug-eluting devices for cancer immunotherapy are discussed. The advantages and limitations of these technologies are evaluated, shedding light on the challenges and opportunities. Having the potential for earlier and more accurate diagnosis, novel therapy methods with better outcomes and less side-effects, more advancement and further breakthroughs can be anticipated in tackling tumours with micro/nanofluidic chips. In future development, it is suggested that combinations of such chips and various other emerging technologies can be attempted and explored for inventing more innovative and functional micro/nanofluidic devices, making a difference in the field of cancer research and therapy. Simultaneously, more improvement such as enhancing reproducibility and affordability is also necessarily required to realise the clinical trial, mass production, commercialisation of these chips.","PeriodicalId":350976,"journal":{"name":"Applied and Computational Engineering","volume":"9 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Current progress in micro/nanofluidic chips and applications in cancer research and therapy\",\"authors\":\"Yixuan Li\",\"doi\":\"10.54254/2755-2721/61/20240916\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Micro/nanofluidic chips have set a new stage for cancer research and therapy, revolutionising the way we detect, diagnose, and treat this formidable disease. This paper provides an overview of the basic properties of micro/nanofluidic chips and current progress in the utilization of micro/nanofluidic chips in the realm of cancer. Their application in DNA and protein analysis, their role in cancer modelling and drug testing, and their innovative use in drug-eluting devices for cancer immunotherapy are discussed. The advantages and limitations of these technologies are evaluated, shedding light on the challenges and opportunities. Having the potential for earlier and more accurate diagnosis, novel therapy methods with better outcomes and less side-effects, more advancement and further breakthroughs can be anticipated in tackling tumours with micro/nanofluidic chips. In future development, it is suggested that combinations of such chips and various other emerging technologies can be attempted and explored for inventing more innovative and functional micro/nanofluidic devices, making a difference in the field of cancer research and therapy. Simultaneously, more improvement such as enhancing reproducibility and affordability is also necessarily required to realise the clinical trial, mass production, commercialisation of these chips.\",\"PeriodicalId\":350976,\"journal\":{\"name\":\"Applied and Computational Engineering\",\"volume\":\"9 2\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied and Computational Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.54254/2755-2721/61/20240916\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied and Computational Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.54254/2755-2721/61/20240916","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

微/纳流控芯片为癌症研究和治疗开创了一个新阶段,彻底改变了我们检测、诊断和治疗这种可怕疾病的方式。本文概述了微型/纳米流体芯片的基本特性以及目前在癌症领域使用微型/纳米流体芯片的进展情况。本文讨论了它们在 DNA 和蛋白质分析中的应用、它们在癌症建模和药物测试中的作用,以及它们在癌症免疫疗法药物洗脱设备中的创新应用。评估了这些技术的优势和局限性,揭示了挑战和机遇。微/纳流控芯片具有更早、更准确诊断的潜力,也是疗效更好、副作用更小的新型治疗方法,预计在利用微/纳流控芯片治疗肿瘤方面会有更多进步和突破。在未来的发展中,建议尝试和探索将此类芯片与其他各种新兴技术相结合,以发明更具创新性和功能性的微/纳流控设备,从而在癌症研究和治疗领域有所作为。同时,要实现这些芯片的临床试验、批量生产和商业化,还必须进行更多改进,如提高可重复性和经济性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Current progress in micro/nanofluidic chips and applications in cancer research and therapy
Micro/nanofluidic chips have set a new stage for cancer research and therapy, revolutionising the way we detect, diagnose, and treat this formidable disease. This paper provides an overview of the basic properties of micro/nanofluidic chips and current progress in the utilization of micro/nanofluidic chips in the realm of cancer. Their application in DNA and protein analysis, their role in cancer modelling and drug testing, and their innovative use in drug-eluting devices for cancer immunotherapy are discussed. The advantages and limitations of these technologies are evaluated, shedding light on the challenges and opportunities. Having the potential for earlier and more accurate diagnosis, novel therapy methods with better outcomes and less side-effects, more advancement and further breakthroughs can be anticipated in tackling tumours with micro/nanofluidic chips. In future development, it is suggested that combinations of such chips and various other emerging technologies can be attempted and explored for inventing more innovative and functional micro/nanofluidic devices, making a difference in the field of cancer research and therapy. Simultaneously, more improvement such as enhancing reproducibility and affordability is also necessarily required to realise the clinical trial, mass production, commercialisation of these chips.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信