主动脉瓣手术后延迟性房室传导阻滞的风险因素:回顾性研究

Qiaoyun Wang, Yuhuan Tian, Yuping Jiang
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摘要

研究目的本研究旨在探讨经导管主动脉瓣置换术(TAVR)后发生迟发性高级别房室传导阻滞(DHAVB)的潜在因素。研究方法对2018年1月至2023年6月期间在青岛市胶州市中心医院接受TAVR的115例患者的临床数据进行回顾性分析。对所有患者进行了术后 30 天的随访观察。根据 DHAVB 发生情况将患者分为两组:DHAVB 组(n = 35)和对照组(n = 80)。比较两组患者术前和术后心脏病的一般临床数据特征。分析TAVR术后与DHAVB相关的风险因素。结果与对照组相比,DHAVB组的平均收缩压(SBP)水平明显升高,而心率(HR)水平则明显降低(P < 0.05)。DHAVB 组的术前平均左心室射血分数(LVEF)明显低于对照组(P < 0.05)。对照组术前 QRS 波增宽、主动脉瓣严重钙化和右束支传导阻滞的发生率明显高于对照组(P < 0.05)。斯皮尔曼相关分析和逻辑回归分析发现,SBP 升高、心率下降、LVEF 降低、术前和术后存在右束支传导阻滞以及室间隔增厚是 TAVR 患者发生 DHAVB 的风险因素(P < 0.05)。结论建议接受 TAVR 的患者密切监测血压、心率和心功能。术前和术后心电图和超声心动图是识别 DHAVB 潜在风险因素的重要工具,为有效的患者预后管理提供了坚实的基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Risk Factors for Delayed Atrioventricular Block after Aortic Valve Surgery: A Retrospective Study
Objective: This study aimed to examine the potential factors that contribute to the occurrence of delayed high-grade atrioventricular block (DHAVB) following transcatheter aortic valve replacement (TAVR). Methods: A retrospective analysis was conducted on the clinical data of 115 patients who underwent TAVR at Jiaozhou Central Hospital of Qingdao Hospital between January 2018, and June 2023. A follow-up period of 30 days post-operation was observed for all patients. The patients were categorized into two groups on the basis of the occurrence of DHAVB: DHAVB group (n = 35) and control group (n = 80). The general clinical data preoperative and postoperative heart disease characteristics of the groups were compared. The risk factors associated with DHAVB after TAVR were analyzed. Results: The mean systolic blood pressure (SBP) level of the DHAVB group significantly increased compared with that of the control group, whereas the heart rate (HR) level significantly reduced (p < 0.05). The average preoperative left ventricular ejection fraction (LVEF) was significantly lower in the DHAVB group than in the control group (p < 0.05). The control group exhibited a significantly higher prevalence of preoperative QRS wave broadening, severe calcification of the aortic valve, and right bundle branch block than the control group (p < 0.05). Spearman's correlation and logistic regression analyses identified increased SBP, decreased HR, diminished LVEF, the presence of preoperative and postoperative right bundle branch block, and thickened interventricular septum were as risk factors for DHAVB in patients undergoing TAVR (p < 0.05). Conclusion: Close surveillance of blood pressure, heart rate, and cardiac function is recommended for individuals undergoing TAVR. Pre-operative and post-operative electrocardiography and echocardiography are valuable tools in identifying potential risk factors for DHAVB, offering a solid foundation for effective patient prognostic management.
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