干细胞血管生成在心肌梗死治疗中的应用:疗效与未来方向

Aayush Arya, Nandhana Parimalam, Arya J. Raut, Prashant Sharma, Ganga Singh
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引用次数: 0

摘要

心肌梗塞(MI)是冠心病的一种严重后果,源于氧气供需失衡。这篇综述阐明了与心肌梗死相关的临床表现、并发症和治疗策略,强调了血管生成在梗死后心肌修复中的关键作用。文章概述了影响心肌梗死后血管生成的因素,以及旨在实现心脏再生的治疗应用。干细胞疗法是一种很有前景的干预方法,它利用各种类型的细胞来加强血管支持和心肌再生。本文研究了心肌梗死后伤口愈合和血管生成的复杂过程,揭示了它们在组织修复中的关键作用。了解这些机制有望推动临床实践中的治疗方法,为改善心肌梗死患者的预后带来希望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Stem Cell Angiogenesis in Myocardial Infraction Treatment: Efficacy and Future Directions
Myocardial infarction (MI) stands as a grave consequence of coronary heart disease, stemming from an imbalance between oxygen demand and supply. This review elucidates the clinical manifestations, complications, and treatment strategies associated with MI, emphasizing the critical role of angiogenesis in myocardial repair post-infarction. Factors influencing angiogenesis following MI are outlined alongside therapeutic applications aimed at cardiac regeneration. Stem-cell therapy emerges as a promising intervention, leveraging various cell types to bolster vascular support and myocardial regeneration. The intricate processes of wound healing and angiogenesis post-MI are examined, shedding light on their pivotal roles in tissue repair. Understanding these mechanisms holds promise for advancing therapeutic approaches in clinical practice, offering hope for improved outcomes in patients with MI.
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