治疗急性偏头痛和识别诱发因素的策略。文献综述

Zuzanna Kotowicz, Jakub Pabiś, Piotr Podgórski, Sandra Górecka, Miłosz Olszański, Aleksander Bogusz, Oskar Kwiatkowski, Anna Kołodziej, Anita Król
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摘要

导言:偏头痛是一种普遍存在的神经系统疾病,影响着全球相当一部分人口,对个人的整体生活质量造成了沉重负担。虽然偏头痛发作的确切病理生理机制仍难以捉摸,但三叉神经通路激活的参与已得到充分证实。已发现多种因素(统称为诱发因素)可诱发偏头痛发作,包括饮食成分、环境刺激(如强光和天气波动)等。偏头痛通常表现为主要位于头部一侧的搏动性疼痛,并经常伴有一系列其他症状,包括畏光、畏声和恶心。偏头痛的治疗需要根据疼痛的具体特点采取多种治疗方法。其中可能包括使用非甾体抗炎药(NSAIDs)、扑热息痛、曲坦类药物和止吐药等。本研究旨在探讨偏头痛发病中最常见的诱发因素以及当代治疗策略,重点是将最新的研究成果和治疗进展纳入这一不断发展的领域。文章使用 PubMed 平台对描述急性偏头痛发作和治疗方法的文献(包括该领域的最新报告)进行了审查。搜索关键词包括 "偏头痛"、"偏头痛诱因"、"三苯氧胺"、"有先兆的偏头痛"。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Strategies for Treating Acute Migraines and Identifying Triggers. Literature review
Introduction Migraine, a prevalent neurological disorder affecting a substantial portion of the global population, poses a significant burden on individuals' overall quality of life. While the exact pathophysiological mechanisms underlying migraine headache attacks remain elusive, the involvement of trigeminal pathway activation is well-documented. A multitude of factors, collectively termed triggers, have been identified as capable of precipitating migraine episodes, ranging from dietary components to environmental stimuli such as bright lights and weather fluctuations. Migraine headaches typically manifest as throbbing pain localized predominantly on one side of the head and are often accompanied by a constellation of additional symptoms including photophobia, phonophobia, and nausea. The management of migraine involves a diverse array of therapeutic modalities tailored to the specific characteristics of the pain experienced. These may include the administration of non-steroidal anti-inflammatory drugs (NSAIDs), paracetamol, triptans, and antiemetics, among others. This study endeavors to explore the most prevalent triggers implicated in migraine onset, as well as contemporary treatment strategies, with an emphasis on incorporating the latest research findings and therapeutic advancements in this evolving field. Aim of the study This review aims to identify symptoms, triggers of acute migraine and solutions in its treatment process, including latest developments. Material and method This article presents the current state of knowledge about acute migraine, triggers and treatment options in various scientific articles. Publications describing acute migraine attacks and treatments including the most recent reports in the field were reviewed using the PubMed platform. The search included the keywords ‘migraine, 'migraine triggers', 'triptans', 'migraine with aura'.
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