改良 ABC 分数阶乳腺癌模型的分析研究

IF 2.4 3区 数学 Q1 MATHEMATICS
Khaled A. Aldwoah, Mohammed A. Almalahi, Manel Hleili, Faez A. Alqarni, Elkhateeb S. Aly, Kamal Shah
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引用次数: 0

摘要

本研究使用修正的 ABC 分数算子研究乳腺癌动力学。我们研究了癌症干细胞、肿瘤细胞、健康细胞、过量雌激素效应和免疫细胞之间的相互作用。通过应用 "紧凑不变集定位 "技术和比较理论,我们建立了没有免疫细胞的癌症持续存在和有免疫反应的癌症根除的条件。我们利用递归序列和定点定理分析了均衡状态、全局吸引持续状态、稳定性、解的唯一性和存在性。利用拉格朗日插值法进行的数值模拟验证并加深了我们对乳腺癌动力学的理解。加入修正的 ABC 分数导数增强了我们对模型的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Analytical study of a modified-ABC fractional order breast cancer model

Analytical study of a modified-ABC fractional order breast cancer model

This study investigates breast cancer dynamics using modified ABC-fractional operators. We examine interactions among cancer stem cells, tumor cells, healthy cells, excess estrogen effects, and immune cells. By applying the “Localization of Compact Invariant Sets” technique and comparison theory, we establish conditions for cancer persistence without immune cells and eradication with an immune response. We analyze equilibria, global attraction persistence state, stability, solution uniqueness, and existence using recursive sequences and fixed point theorem. Numerical simulations with Lagrange’s interpolation validate and deepen our understanding of breast cancer dynamics. Incorporating modified ABC-fractional derivatives enhances our comprehension of the model.

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来源期刊
Journal of Applied Mathematics and Computing
Journal of Applied Mathematics and Computing Mathematics-Computational Mathematics
CiteScore
4.20
自引率
4.50%
发文量
131
期刊介绍: JAMC is a broad based journal covering all branches of computational or applied mathematics with special encouragement to researchers in theoretical computer science and mathematical computing. Major areas, such as numerical analysis, discrete optimization, linear and nonlinear programming, theory of computation, control theory, theory of algorithms, computational logic, applied combinatorics, coding theory, cryptograhics, fuzzy theory with applications, differential equations with applications are all included. A large variety of scientific problems also necessarily involve Algebra, Analysis, Geometry, Probability and Statistics and so on. The journal welcomes research papers in all branches of mathematics which have some bearing on the application to scientific problems, including papers in the areas of Actuarial Science, Mathematical Biology, Mathematical Economics and Finance.
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