等待心脏手术长达一年的风险。

Márcio Madeira, Jose Neves, Tiago Nolasco, Marta Marques, Miguel Abecasis, Miguel Sousa-Uva
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引用次数: 0

摘要

导言心脏病与死亡风险相关,既与心脏病有关,也与合并症有关。等待手术的时间从出现症状开始,包括转诊、完成诊断和手术候诊(SWL)。这项研究是在 COVID-19 大流行期间进行的,当时手术能力和患者发病率都受到了影响:该队列包括 1914 名连续的成年患者(36.6% 为女性,平均年龄为 67 ± 11 岁),他们于 2019 年 1 月至 2021 年 12 月期间在官方 SWL 上进行了前瞻性登记。我们分析了从 4 天到 1 年的候诊时间,以排除急诊和异常值。优先顺序按照国家非肿瘤或肿瘤手术标准进行分类:研究期间,74%的患者接受了手术,19.2%的患者仍在等待,4.3%的患者放弃了手术。大多数病例为瓣膜手术(41.2%)或单独的旁路手术(34.2%)。29.7%的患者被划分为非优先患者,61.8%的患者被划分为优先患者,8.6%的患者被划分为高度优先患者,各组间的SWL平均时间存在显著差异(p结论:2021 年观察到的风险增加可能与大流行有关,因为等待时间延长或直接导致死亡。由于风险分层并不完全准确,因此等待时间成为影响死亡率的最关键因素,实施更严格的时间限制可能会降低死亡率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Risk Of Waiting Up To One Year For Cardiac Surgery.

Introduction: Cardiac disease is associated with a risk of death, both by the cardiac condition and by comorbidities. The waiting time for surgery begins with the onset of symptoms and includes referral, completion of the diagnosis and surgical waiting list (SWL). This study was conducted during the COVID-19 pandemic, which affected surgical capacity and patients' morbidities.

Methods: The cohort includes 1914 consecutive adult patients (36.6% women, mean age 67 ±11 years), prospectively registered in the official SWL from January 2019 to December 2021. We analyzed waiting times ranging from 4 days to one year to exclude urgencies and outliers. Priority was classified by the national criteria for non-oncologic or oncology surgery.

Results: During the study period, 74% of patients underwent surgery, 19.2% were still waiting, and 4.3% dropped out. Most cases were valvular (41.2%) or isolated bypass procedures (34.2%). Patients were classified as non-priority in 29.7%, priority in 61.8%, and high priority in 8.6%, with significantly different SWL mean times between groups (p<0.001). The overall mean waiting time was 167 ± 135 days. Mortality on SWL was 2.5%, or 1.1 deaths per patient/weeks. There were two mortality independent predictors: age (HR 1.05) and the year 2021 versus 2019 (HR 2.07) and a trend toward higher mortality in priority patients versus non-priority (p=0.065). The overall risk increased with time with different slopes for each year. Using the time limits for SWL in oncology, there would have been a significant risk reduction (p=0.011).

Conclusion: The increased risk observed in 2021 may be related to the pandemic, either by increasing waiting time or by direct mortality. Since risk stratification is not entirely accurate, waiting time emerges as the most crucial factor influencing mortality, and implementing stricter time limits could have led to lower mortality rates.

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