对两名巨型实体血管母细胞瘤患者进行术前栓塞的多模式治疗。

Surgical neurology international Pub Date : 2024-04-26 eCollection Date: 2024-01-01 DOI:10.25259/SNI_28_2024
John Vargas-Urbina, John Alex Crisanto-Silva, Carlos Vásquez-Perez, Aarón Davila-Adrianzén, Daniel Alcas-Seminario, William Lines-Aguilar, Rocio Mamani-Choquepata, Giuseppe Panta-Rojas
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引用次数: 0

摘要

背景:血管母细胞瘤是一种良性血管肿瘤,属于世界卫生组织I级肿瘤,最常发生于小脑。由于出血过多,完全的显微手术切除可能是一项挑战,因此术前栓塞治疗非常重要:病例描述:本报告介绍了两例临床病例,一名是 25 岁的女性,另一名是 75 岁的男性,他们因梗阻性脑积水而出现颅内高压症状;两例病例均放置了脑室腹腔分流术;此外,他们还出现了小脑体征。两人都接受了乙烯-乙烯醇共聚物栓塞治疗,血流减少。之后,他们在栓塞后一周内接受了显微外科切除术,两例患者均获得了大体全切除,无血流动力学并发症,临床症状改善,手术效果良好。值得一提的是,手术治疗是黄金标准,可以采用合适的手术方法,就像我们的患者一样,我们为其实施了侧枕下开颅手术:结论:实性血管母细胞瘤的发病率低于囊性血管母细胞瘤。实性血管母细胞瘤的发病率低于囊性血管母细胞瘤,治疗方法是手术切除,这是一项挑战,在手术计划中必须始终将其视为动静脉畸形,包括术前栓塞,以降低围手术期的发病率和死亡率,获得良好的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Multimodal management of giant solid hemangioblastomas in two patients with preoperative embolization.

Background: Hemangioblastomas are benign vascular neoplasms, World Health Organization grade I, with the most frequent location in the cerebellum. Complete microsurgical resection can be a challenge due to excessive bleeding, which is why preoperative embolization takes importance.

Case description: Two clinical cases are presented, a 25-year-old woman and a 75-year-old man, who presented with intracranial hypertension symptoms due to obstructive hydrocephalus; a ventriculoperitoneal shunt was placed in both cases; in addition, they presented with cerebellar signs. Both underwent embolization with ethylene vinyl alcohol copolymer, with blood flow reduction. After that, they underwent microsurgical resection within the 1st-week post embolization, obtaining, in both cases, gross total resection without hemodynamic complications, with clinical improvement and good surgical outcome. It is worth mentioning that surgical management is the gold standard that allows a suitable surgical approach, like in our patients, for which a lateral suboccipital craniotomy was performed.

Conclusion: Solid hemangioblastomas are less frequent than their cystic counterparts. The treatment is the surgical resection, which is a challenge and always has to be considered as an arteriovenous malformation in the surgical planning, including preoperative embolization to reduce perioperative morbidity and mortality and get good outcomes.

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